Mesothelin Protein (MSLN) (Fc Tag)
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- 抗原 See all Mesothelin (MSLN) 蛋白
- Mesothelin (MSLN)
- 蛋白类型
- Recombinant
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宿主
- Cynomolgus
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资源
- HEK-293 Cells
- 标记
- This Mesothelin protein is labelled with Fc Tag.
- 序列
- Asp296-Gly580
- 纯度
- > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus MSLN, hFc Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-MSLN Antibody, hFc Tag with the EC50 of 47.1ng/ml determined by ELISA. See testing image for detail.
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Mesothelin (MSLN) protein (Fc-Avi Tag,Biotin)
MSLN 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Mesothelin (MSLN) (AA 296-580) protein (Fc Tag)MSLN 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Mesothelin (MSLN) (AA 296-580) protein (His-Avi Tag)MSLN 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Mesothelin (MSLN) protein (His tag)MSLN 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Mesothelin (MSLN) protein (His-Avi Tag,Biotin)MSLN 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Mesothelin (MSLN) (AA 406-690) protein (His tag,Biotin)MSLN 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Mesothelin (MSLN) protein (His tag)MSLN 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Mesothelin (MSLN) (AA 296-580) protein (mFc-His Tag)MSLN 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. WB
Mesothelin (MSLN) (AA 1-621) protein (GST tag)MSLN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Mesothelin (MSLN) (AA 464-563) protein (GST tag)MSLN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Mesothelin (MSLN)
- 别名
- MSLN (MSLN 产品)
- 别名
- MPF Protein, SMRP Protein, MSLN Protein, mesothelin Protein, MSLN Protein, Msln Protein, LOC611363 Protein, LOC100524016 Protein
- 背景
- MSLN, CAK1 antigen, CAK1, megakaryocyte potentiating factor, Mesothelin, MPF, MPFSMRP,Pre-pro-megakaryocyte-potentiating factor, SMR, soluble MPF mesothelin related protein,Mesothelin, also known as MSLN, is a protein that in humans is encoded by the MSLN gene.Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31- kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known.A knockout mouse line that lacks mesothelin reproduces and develops normally.
- 分子量
- 58.6 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
- 途径
- EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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