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Mesothelin 产品

(Mesothelin (MSLN))

Categories

This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].

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Featured Mesothelin Categories

Mesothelin 抗体

High quality antibodies with extensive validation data.

Mesothelin ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Mesothelin 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Mesothelin 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC (f)
Validations
  • (7)
Cat. No. ABIN6939032
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, FACS, IHC (p)
Validations
  • (5)
Cat. No. ABIN727608
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC (f)
Validations
  • (5)
Cat. No. ABIN7504135
Quantity 100 μg
Datasheet Datasheet

Recommended Mesothelin ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6957762
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6957761
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6976025
Quantity 96 tests
Datasheet Datasheet

Recommended Mesothelin 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7275282
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7275288
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7275283
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Mesothelin Products

Li, Li, Xu, Xing, Ding, Jing, Wang, Hong: "Preclinical evaluation of a novel anti-mesothelin immunotoxin based on a single domain antibody as the targeting ligand." in: International journal of pharmaceutics, Vol. 602, pp. 120647, (2021) (PubMed).

Duong, Wu, Green, Bavaghar-Zaeimi, Wang, Labib, Zhou, Cantu, Jeganathan, Popescu, Pantea, de Perrot, Kelley: "A liquid biopsy for detecting circulating mesothelial precursor cells: A new biomarker for diagnosis and prognosis in mesothelioma." in: EBioMedicine, Vol. 61, pp. 103031, (2021) (PubMed).

Makita, Kunii, Sakurai, Ihara, Motohashi, Suzuki, Nakayama, Okamoto: "Activated iNKT cells enhance the anti-tumor effect of antigen specific CD8 T cells on mesothelin-expressing salivary gland cancer." in: BMC cancer, Vol. 18, Issue 1, pp. 1254, (2019) (PubMed).

Hung, Xu, Li, Ma, Jin, Viley, Allen, Natarajan, Shivakumar, Peshwa, Emens: "Development of Anti-Human Mesothelin-Targeted Chimeric Antigen Receptor Messenger RNA-Transfected Peripheral Blood Lymphocytes for Ovarian Cancer Therapy." in: Human gene therapy, Vol. 29, Issue 5, pp. 614-625, (2019) (PubMed).

Sirois, Deny, Li, Fall, Moore: "Engineered Fn3 protein has targeted therapeutic effect on mesothelin-expressing cancer cells and increases tumor cell sensitivity to chemotherapy." in: Biotechnology and bioengineering, (2019) (PubMed).

Zhang, Yang, Gu, Wu, Chi, Liu, Wang, Xue, Qi, Sun, Zhang, Hu, Xu: "Recombination of a dual-CAR-modified T lymphocyte to accurately eliminate pancreatic malignancy." in: Journal of hematology & oncology, Vol. 11, Issue 1, pp. 102, (2018) (PubMed).

Zhang, Khanna, Jiang, Alewine, Miettinen, Pastan, Hassan: "Efficacy of Anti-mesothelin Immunotoxin RG7787 plus Nab-Paclitaxel against Mesothelioma Patient-Derived Xenografts and Mesothelin as a Biomarker of Tumor Response." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 23, Issue 6, pp. 1564-1574, (2018) (PubMed).

Oehl, Kresoja-Rakic, Opitz, Vrugt, Weder, Stahel, Wild, Felley-Bosco: "Live-Cell Mesothelioma Biobank to Explore Mechanisms of Tumor Progression." in: Frontiers in oncology, Vol. 8, pp. 40, (2018) (PubMed).

Sirois, Deny, Baierl, George, Moore: "Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding." in: PLoS ONE, Vol. 13, Issue 5, pp. e0197029, (2018) (PubMed).

Tang, Yang, Wang, Gu, Xia, Feng, Yang, Zhao, Su, Su, Wang: "Nucleoside reverse transcriptase inhibitor-induced rat oocyte dysfunction and low fertility mediated by autophagy." in: Oncotarget, Vol. 9, Issue 3, pp. 3895-3907, (2018) (PubMed).

Synonyms and alternative names related to Mesothelin

mesothelin (MSLN), mesothelin (Msln), mesothelin (LOC611363), mesothelin (LOC100524016), MPF, MSLN, SMRP

Protein level used designations for Mesothelin

  • CAK1 antigen
  • megakaryocyte potentiating factor
  • pre-pro-megakaryocyte-potentiating factor
  • soluble MPF mesothelin related protein
  • ERC/mesothelin
  • protein expressed in renal carcinoma
  • mesothelin
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