Menin 产品
(Multiple Endocrine Neoplasia 1 (MEN1))
Categories
This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008].
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Featured Menin Categories
Menin 抗体
High quality antibodies with extensive validation data.
Menin ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Menin 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Menin 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (5)
Cat. No.
ABIN2682998
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN676343
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7443704
Quantity
100 μL
Datasheet
Datasheet
Recommended Menin ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1142130
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1142131
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1142132
Quantity
96 tests
Datasheet
Datasheet
Recommended Menin 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310714
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310718
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3132147
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Menin Products
: "MEN1 is a melanoma tumor suppressor that preserves genomic integrity by stimulating transcription of genes that promote homologous recombination-directed DNA repair." in: Molecular and cellular biology, Vol. 33, Issue 13, pp. 2635-47, (2013) (PubMed).: "Phosphorylated olig1 localizes to the cytosol of oligodendrocytes and promotes membrane expansion and maturation." in: Glia, Vol. 60, Issue 9, pp. 1427-36, (2012) (PubMed).
: "Genome-wide characterization of menin-dependent H3K4me3 reveals a specific role for menin in the regulation of genes implicated in MEN1-like tumors." in: PLoS ONE, Vol. 7, Issue 5, pp. e37952, (2012) (PubMed).
: "The negative feedback-loop between the oncomir Mir-24-1 and menin modulates the Men1 tumorigenesis by mimicking the "Knudson's second hit"." in: PLoS ONE, Vol. 7, Issue 6, pp. e39767, (2012) (PubMed).
: "Conditional deletion of menin results in antral G cell hyperplasia and hypergastrinemia." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 303, Issue 6, pp. G752-64, (2012) (PubMed).
: "Tumor suppressor menin mediates peripheral nerve injury-induced neuropathic pain through potentiating synaptic plasticity." in: Neuroscience, Vol. 223, pp. 473-85, (2012) (PubMed).
: "Insulin regulates menin expression, cytoplasmic localization, and interaction with FOXO1." in: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 3, pp. E474-83, (2011) (PubMed).
: "Regulation of cyclin B2 expression and cell cycle G2/m transition by menin." in: The Journal of biological chemistry, Vol. 285, Issue 24, pp. 18291-300, (2010) (PubMed).
: "Multiple endocrine neoplasia type 1 deletion in pancreatic alpha-cells leads to development of insulinomas in mice." in: Endocrinology, Vol. 151, Issue 8, pp. 4024-30, (2010) (PubMed).
: "MEN1 in pancreatic endocrine tumors: analysis of gene and protein status in 169 sporadic neoplasms reveals alterations in the vast majority of cases." in: Endocrine-related cancer, Vol. 17, Issue 3, pp. 771-83, (2010) (PubMed).
Synonyms and alternative names related to Menin
menin 1 (MEN1), menin 1 (men1), menin 1 L homeolog (men1.L), multiple endocrine neoplasia I (men1), multiple endocrine neoplasia 1 (Men1), menin 1 (Men1), AW045611, MEAI, meai, menin, SCG2, scg2Protein level used designations for Menin
- menin
- multiple endocrine neoplasia protein
- multiple endocrine neoplasia 1
- multiple endocrine neoplasia I
- menin-like
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