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MET 产品

(Enkephalin (MET))

Categories

Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'- [CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, promotes cells to enter into S phase and proliferation (By similarity).

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Featured MET Categories

MET 抗体

High quality antibodies with extensive validation data.

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Recommended MET ELISA试剂盒

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Latest Publications for our MET Products

Brestoff, Kim, Saenz, Stine, Monticelli, Sonnenberg, Thome, Farber, Lutfy, Seale, Artis: "Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity." in: Nature, (2015) (PubMed).

Mosnaim, Maturana, Callaghan, Wolf: "Changes in plasma methionine-enkephalin levels associated with a cluster headache episode." in: American journal of therapeutics, Vol. 20, Issue 5, pp. 463-8, (2014) (PubMed).

Lu, Evans, Hirano, Liu: "Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 1, pp. E168-77, (2014) (PubMed).

Tao, Tao, Chen, Yang, Lu, Sun, Huang, Yu: "Proteinase-activated receptor 1 contributed to up-regulation of enkephalin in keratinocytes of patients with obstructive jaundice." in: Anesthesiology, Vol. 121, Issue 1, pp. 127-39, (2014) (PubMed).

McLeod, Kobayashi, Sen, Baghbaderani, Sadi, Ulalia, Behie, Mendez: "Transplantation of GABAergic cells derived from bioreactor-expanded human neural precursor cells restores motor and cognitive behavioral deficits in a rodent model of Huntington's disease." in: Cell transplantation, Vol. 22, Issue 12, pp. 2237-56, (2014) (PubMed).

Kupchik, Kalivas: "The rostral subcommissural ventral pallidum is a mix of ventral pallidal neurons and neurons from adjacent areas: an electrophysiological study." in: Brain structure & function, Vol. 218, Issue 6, pp. 1487-500, (2013) (PubMed).

Riters, Ellis, Angyal, Borkowski, Cordes, Stevenson: "Links between breeding readiness, opioid immunolabeling, and the affective state induced by hearing male courtship song in female European starlings (Sturnus vulgaris)." in: Behavioural brain research, Vol. 247, pp. 117-24, (2013) (PubMed).

Nakamura, Tomida, Yamamoto, Ando, Takamata, Kondo, Kurasawa, Asanuma: "The endogenous opioids related with antinociceptive effects induced by electrical stimulation into the amygdala." in: The open dentistry journal, Vol. 7, pp. 27-35, (2013) (PubMed).

Kelm-Nelson, Stevenson, Cordes, Riters: "Modulation of male song by naloxone in the medial preoptic nucleus." in: Behavioral neuroscience, Vol. 127, Issue 3, pp. 451-7, (2013) (PubMed).

deCampo, Fudge: "Amygdala projections to the lateral bed nucleus of the stria terminalis in the macaque: comparison with ventral striatal afferents." in: The Journal of comparative neurology, Vol. 521, Issue 14, pp. 3191-216, (2013) (PubMed).

Synonyms and alternative names related to MET

proenkephalin (PENK), proenkephalin (Penk), Enk, Penk-rs, Penk1, Penk2

Protein level used designations for MET

  • enkephalin
  • preproenkephalin 2
  • proenkephalin 1
  • proenkephalin 2
  • proenkephalin related sequence
  • proenkephalin-A
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