电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

LTBR Protein (AA 31-227) (Fc Tag)

LTBR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7275218
发货至: 中国
  • 抗原 See all LTBR 蛋白
    LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))
    蛋白类型
    Recombinant
    产品特性
    AA 31-227
    宿主
    • 14
    • 7
    • 2
    资源
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This LTBR protein is labelled with Fc Tag.
    原理
    Human LTBR Protein
    序列
    Gln31-Met227
    产品特性
    Recombinant Human LTBR Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln31-Met227.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human LIGHT, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Human LTBR, hFc Tag with the EC50 22.9ng/ml determined by ELISA. See testing image for detail.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))
    别名
    LTBR (LTBR 产品)
    别名
    AI256028 Protein, CD18 Protein, LTbetaR Protein, Ltar Protein, TNF-R-III Protein, TNFCR Protein, TNFR-RP Protein, TNFR2-RP Protein, TNFRrp Protein, Tnfbr Protein, Tnfrsf3 Protein, D12S370 Protein, LT-BETA-R Protein, TNFR3 Protein, TNFRSF3 Protein, lymphotoxin beta receptor Protein, lymphotoxin B receptor Protein, Ltbr Protein, LTBR Protein
    背景
    Components of lymphotoxin beta receptor (LTBR)-associated signaling complexes, including TRAF2, TRAF3, NIK, IKK1, and IKK2 have been shown to participate in the coupling of LTBR to NFkappaB.TRAF3 functions as a negative regulator of LTBR signaling via both canonical and non-canonical NFkappaB pathways by two distinct mechanisms. These effects of TRAF3 depletion did not require LTBR signaling and were consistent with autonomous activation of the non-canonical NFkappaB pathway.
    分子量
    48.5 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
    途径
    NF-kappaB Signaling
You are here: