LILRA4 Protein (AA 24-446) (His-Avi Tag,Biotin)
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- 抗原 See all LILRA4 蛋白
- LILRA4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 4 (LILRA4))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-446
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This LILRA4 protein is labelled with His-Avi Tag,Biotin.
- 原理
- Biotinylated Human LILRA4/CD85g Protein
- 序列
- Glu24-Asn446
- 产品特性
- Recombinant Biotinylated Human LILRA4/CD85g Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu24-Asn446.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
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- Discover our top product LILRA4 蛋白
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Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 4 (LILRA4) protein (His tag)
LILRA4 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 4 (LILRA4) (AA 24-446) protein (His-Avi Tag)LILRA4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 4 (LILRA4) (AA 1-499) protein (GST tag)LILRA4 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- LILRA4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 4 (LILRA4))
- 别名
- LILRA4 (LILRA4 产品)
- 别名
- ILT7 Protein, CD85g Protein, leukocyte immunoglobulin like receptor A4 Protein, LILRA4 Protein
- 背景
- LILRA4, also known as ILT7 and CD85g, is an approximately 60-70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA4 consists of a 423 amino acid (aa) extracellular domain (ECD) with four immunoglobulin-like domains, a 21 aa transmembrane segment, and a 32 aa cytoplasmic domain.LILRA4 function coreceptor to limit the innate immune responses to viral infections, signaling occurs via FCER1G (PubMed:16735691, PubMed:19564354). Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades.
- 分子量
- 49.5 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
- UniProt
- P59901
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