LGR5 Protein (AA 22-543) (Fc Tag)
LGR5
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE
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- 抗原 See all LGR5 蛋白
- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-543
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This LGR5 protein is labelled with Fc Tag.
- 原理
- Human LGR-5 Protein
- 序列
- Gly22-Pro543
- 产品特性
- Recombinant Human LGR-5 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gly22-Pro543.
- 纯度
- > 95 % as determined by Tris-Bis PAGE
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
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Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 22-561) (Active) protein (His tag)
LGR5 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 22-561) protein (His tag)LGR5 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS, 5 mM DTT ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
- 别名
- LGR-5 (LGR5 产品)
- 别名
- lgr5-a Protein, lgr5a Protein, FEX Protein, Gpr49 Protein, GPR49 Protein, GPR67 Protein, GRP49 Protein, HG38 Protein, leucine-rich repeat containing G protein-coupled receptor 5 L homeolog Protein, leucine rich repeat containing G protein coupled receptor 5 Protein, leucine rich repeat containing G protein-coupled receptor 5 Protein, lgr5.L Protein, Lgr5 Protein, LGR5 Protein
- 背景
- G protein-coupled receptor 5 (LGR5), known as a stem cell marker for colon cancer and gastric cancer, can serve as a novel GSC marker involved in EMT and a therapeutic target in glioma.LGR5 is a new functional GSC marker and prognostic indicator that can promote EMT by activating the Wnt/β-catenin pathway and would thus be a novel therapeutic target for glioma.
- 分子量
- 85 kDa. Due to glycosylation, the protein migrates to 110-120 kDa based on Tris-Bis PAGE result.
- 途径
- WNT signaling
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