IL23R Protein (AA 24-355) (His tag)
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- 抗原 See all IL23R 蛋白
- IL23R (Interleukin 23 Receptor (IL23R))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-355
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL23R protein is labelled with His tag.
- 原理
- Human IL-23R Protein
- 序列
- Gly24-Gly355
- 产品特性
- Recombinant Human IL-23R Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly24-Gly355.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-23R, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human IL-23 alpha&IL-12 beta, His Tag with the EC50 of 1.15μg/ml determined by ELISA. The affinity constant of 5.72 nM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product IL23R 蛋白
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Interleukin 23 Receptor (IL23R) (AA 24-355) protein (mFc Tag)
IL23R 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 23 Receptor (IL23R) (AA 24-374) protein (His tag)IL23R 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 23 Receptor (IL23R) (AA 24-354) protein (His tag)IL23R 宿主: 犬 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 23 Receptor (IL23R) (AA 24-353) protein (His tag)IL23R 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 23 Receptor (IL23R) (AA 24-355) (Active) protein (Fc Tag,AVI tag,Biotin)IL23R 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 23 Receptor (IL23R) protein (Fc Tag)IL23R 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Interleukin 23 Receptor (IL23R) (Active) protein (Fc Tag)IL23R 宿主: 大鼠 宿主: HEK-293 Cells Recombinant (75.1+16.6) as determined by SDS-PAGE Active
Interleukin 23 Receptor (IL23R) (AA 553-628) protein (GST tag)IL23R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 23 Receptor (IL23R) (AA 377-629) protein (His tag)Crystallography grade IL23R 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 23 Receptor (IL23R) (AA 396-644) protein (His tag)Crystallography grade IL23R 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- IL23R (Interleukin 23 Receptor (IL23R))
- 别名
- IL-23R (IL23R 产品)
- 别名
- IL-23R Protein, IL23R Protein, il-23r Protein, interleukin 23 receptor Protein, IL23R Protein, il23r Protein, Il23r Protein
- 背景
- Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The functional IL-23 receptor complex consists of two receptor subunits, the IL-12 receptor beta 1 subunit (IL-12 R beta 1) and the IL-23-specific receptor subunit (IL-23 R).This receptor associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade.
- 分子量
- 39.15 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Tris-Bis PAGE result.
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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