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- 抗原 See all IL23R 蛋白
- IL23R (Interleukin 23 Receptor (IL23R))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- 人细胞
- 标记
- This IL23R protein is labelled with Fc Tag.
- 原理
- Recombinant Mouse IL-23 Receptor/IL-23R Protein (Fc Tag)
- 序列
- Gly24-Asp372
- 产品特性
- Recombinant Mouse Interleukin-23 Receptor is produced by our Mammalian expression system and the target gene encoding Gly24-Asp372 is expressed with a Fc tag at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product IL23R 蛋白
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Interleukin 23 Receptor (IL23R) (AA 24-355) protein (mFc Tag)
IL23R 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 23 Receptor (IL23R) (AA 24-355) protein (His tag)IL23R 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 23 Receptor (IL23R) (AA 24-374) protein (His tag)IL23R 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 23 Receptor (IL23R) (AA 24-354) protein (His tag)IL23R 宿主: 犬 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 23 Receptor (IL23R) (AA 24-353) protein (His tag)IL23R 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 23 Receptor (IL23R) (AA 24-355) (Active) protein (Fc Tag,AVI tag,Biotin)IL23R 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 23 Receptor (IL23R) (Active) protein (Fc Tag)IL23R 宿主: 大鼠 宿主: HEK-293 Cells Recombinant (75.1+16.6) as determined by SDS-PAGE Active
Interleukin 23 Receptor (IL23R) (AA 553-628) protein (GST tag)IL23R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 23 Receptor (IL23R) (AA 377-629) protein (His tag)Crystallography grade IL23R 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 23 Receptor (IL23R) (AA 396-644) protein (His tag)Crystallography grade IL23R 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- IL23R (Interleukin 23 Receptor (IL23R))
- 别名
- IL-23 Receptor/IL-23R (IL23R 产品)
- 别名
- IL-23R Protein, IL23R Protein, il-23r Protein, interleukin 23 receptor Protein, IL23R Protein, il23r Protein, Il23r Protein
- 背景
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Background: Interleukin 23 receptor (IL23R), a heterodimer of the IL12 receptor β1 (IL12Rβ1) and IL12Rβ2, is a type I cytokine receptor for IL23. IL23R is comprised of two subunits, the IL12Rβ1 subunit, which is shared with several cytokines, and a subunit that is unique to IL-23. IL23, after binding to IL23R, activates memory T cells and mediates pro-inflammatory activities in part by the production of IL17 through activation of TH17 lymphocytes. IL23R is expressed on T cells, NK cells, dendritic cells, and macrophages. In fact, polymorphisms of the IL23R gene were reported to be associated with susceptibility to inflammatory diseases and autoimmune diseases such as psoriasis, multiple sclerosis, Graves's ophtalmopathy and inflammatory bowel diseases. The IL23R is known to be critically involved in the carcinogenesis of different malignant tumor.
Synonym: Interleukin-23 receptor, Il23r, IL-23 receptor, IL-23R, interleukin 23 receptor
- 分子量
- 67.3 kDa
- UniProt
- Q8K4B4
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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