IL11RA Protein (AA 24-370) (His tag)
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- 抗原 See all IL11RA 蛋白
- IL11RA (Interleukin 11 Receptor, alpha (IL11RA))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-370
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL11RA protein is labelled with His tag.
- 原理
- Human IL-11R alpha Protein
- 序列
- Ser24-Ala370
- 产品特性
- Recombinant Human IL-11R alpha Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser24-Ala370.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 1.86 nM as determined in SPR assay (Biacore T200). See testing image for detail.
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Interleukin 11 Receptor, alpha (IL11RA) (AA 24-372) protein (His tag)
IL11RA 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 11 Receptor, alpha (IL11RA) (AA 145-362) protein (His-IF2DI Tag)IL11RA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 11 Receptor, alpha (IL11RA) (AA 1-422) protein (GST tag)IL11RA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 11 Receptor, alpha (IL11RA) (Active) protein (His tag)IL11RA 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
Interleukin 11 Receptor, alpha (IL11RA) (AA 24-370) (Active) protein (Fc Tag)IL11RA 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- IL11RA (Interleukin 11 Receptor, alpha (IL11RA))
- 别名
- IL-11R alpha (IL11RA 产品)
- 别名
- CRSDA Protein, fi26e06 Protein, il-11ra Protein, wu:fi26e06 Protein, AI314697 Protein, GP130 Protein, Il-11ra Protein, Il11ra Protein, Il11ra2 Protein, NR1 Protein, interleukin 11 receptor subunit alpha Protein, interleukin 11 receptor, alpha Protein, interleukin 11 receptor subunit alpha 1 Protein, interleukin 11 receptor, alpha chain 1 Protein, IL11RA Protein, il11ra Protein, Il11ra1 Protein, Il11ra Protein
- 背景
- Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. IL-11 and its receptor, IL-11Ra, are expressed in human cancers,human cancer cells expressed a functional IL-11Ra subunit, which triggered signal transduction either by exogenous recombinant human IL-11 or by autocrine production of IL-11 in cells cultured under hypoxic conditions.
- 分子量
- 38.8 kDa. Due to glycosylation, the protein migrates to 50-55 kDa based on Tris-Bis PAGE result.
- 途径
- JAK/STAT Signaling, Growth Factor Binding
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