IL17C Protein (AA 19-197) (His-Avi Tag)
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- 抗原 See all IL17C 蛋白
- IL17C (Interleukin 17C (IL17C))
- 蛋白类型
- Recombinant
- 产品特性
- AA 19-197
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL17C protein is labelled with His-Avi Tag.
- 原理
- Human IL-17C Protein
- 序列
- His19-Val197
- 产品特性
- Recombinant Human IL-17C Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His19-Val197.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-17C at 5μg/ml (100μl/Well) on the plate. Dose response curve for Human IL-17R alpha, hFc Tag with the EC50 of 2.6μg/ml determined by ELISA. See testing image for detail.
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Interleukin 17C (IL17C) (AA 1-197) protein (GST tag)
IL17C 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 17C (IL17C) (AA 19-197) protein (His tag)Crystallography grade IL17C 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 17C (IL17C) (AA 17-194) protein (His tag)Crystallography grade IL17C 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 17C (IL17C) (AA 19-197) (Active) protein (His tag)IL17C 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 17C (IL17C) (AA 19-197) (Active) protein (His tag,AVI tag,Biotin)IL17C 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 17C (IL17C) proteinIL17C 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant WB, SDS, ELISA, IP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 50 mM MES, 150 mM NaCl (PH 6.0).
- 缓冲液
- Lyophilized from 0.22μm filtered solution in 50 mM MES, 150 mM NaCl (PH 6.0). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- IL17C (Interleukin 17C (IL17C))
- 别名
- IL-17C (IL17C 产品)
- 别名
- IL17C Protein, il17-3 Protein, CX2 Protein, IL-17C Protein, IL-21 Protein, interleukin 17C Protein, interleukin 17c Protein, IL17C Protein, il17c Protein, Il17c Protein
- 背景
- Interleukin-17C (IL-17C) is a 15-20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. The six IL-17 cytokines (IL-17A-F) are encoded by separate genes but adopt a conserved cystine knot fold. IL-17C is Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G.
- 分子量
- 22.6 kDa. Due to glycosylation, the protein migrates to 25 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9P0M4
- 途径
- Cellular Response to Molecule of Bacterial Origin
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