IL17C Protein (AA 19-197) (His tag,AVI tag,Biotin)
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- 抗原 See all IL17C 蛋白
- IL17C (Interleukin 17C (IL17C))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 19-197
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL17C protein is labelled with His tag,AVI tag,Biotin.
- 序列
- AA 19-197
- 特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product IL17C 蛋白
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Interleukin 17C (IL17C) (AA 19-197) protein (His-Avi Tag)
IL17C 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
Interleukin 17C (IL17C) (AA 1-197) protein (GST tag)IL17C 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 17C (IL17C) (AA 19-197) protein (His tag)Crystallography grade IL17C 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 17C (IL17C) (AA 17-194) protein (His tag)Crystallography grade IL17C 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 17C (IL17C) (AA 19-197) (Active) protein (His tag)IL17C 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 17C (IL17C) proteinIL17C 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant WB, SDS, ELISA, IP
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- 说明
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Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- IL17C (Interleukin 17C (IL17C))
- 别名
- IL-17C (IL17C 产品)
- 别名
- IL17C Protein, il17-3 Protein, CX2 Protein, IL-17C Protein, IL-21 Protein, interleukin 17C Protein, interleukin 17c Protein, IL17C Protein, il17c Protein, Il17c Protein
- 背景
- Interleukin-17C(IL-17C) is a glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. IL-17C binds to IL-17 RE with high affinity and to IL-17 RA with low affinity, binds to a heterodimer formed by IL17RA and IL17RE. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes.
- 分子量
- 23.4 kDa
- NCBI登录号
- NP_037410
- 途径
- Cellular Response to Molecule of Bacterial Origin
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