IL-25 Protein (AA 33-177) (His-Avi Tag,Biotin)
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- 抗原 See all IL-25 (IL25) 蛋白
- IL-25 (IL25) (Interleukin 25 (IL25))
- 蛋白类型
- Recombinant
- 产品特性
- AA 33-177
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL-25 protein is labelled with His-Avi Tag,Biotin.
- 原理
- Biotinylated Human IL-25/IL-17E Protein
- 序列
- Tyr33-Gly177
- 产品特性
- Recombinant Biotinylated Human IL-25/IL-17E Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Tyr33-Gly177.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-17RB, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human IL-25, His Tag with the EC50 of 58.5ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product IL25 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- 储存条件
- -80 °C
- 储存方法
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- IL-25 (IL25) (Interleukin 25 (IL25))
- 别名
- IL-25 (IL25 产品)
- 别名
- IL17E Protein, IL-17e Protein, Il17e Protein, IL25 Protein, RGD1561632 Protein, interleukin 25 Protein, IL25 Protein, Il25 Protein
- 背景
- IL-25, also known as IL-17E, is a member of the IL-17 cytokine family mostly produced by epithelial cells and innate immune cells. After binding to the IL-17RB/IL-17RA complex, IL-25 induces downstream signaling responses in epithelial cells and type 2 lymphocytes, which initiates, propagates, and sustains type 2 immunity. The function of IL-25 in allergic diseases such as asthma has been well established, and now also is extended to diseases such as inflammatory bowel disease and cancer.
- 分子量
- 19.24 kDa. Due to glycosylation, the protein migrates to 25-35 kDa based on Tris-Bis PAGE result.
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