ICAM1 Protein (AA 28-480) (His tag)
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- 抗原 See all ICAM1 蛋白
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 28-480
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ICAM1 protein is labelled with His tag.
- 原理
- Human ICAM-1/CD54 Protein
- 序列
- Gln28-Glu480
- 产品特性
- Recombinant Human ICAM-1/CD54 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln28-Glu480.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human ICAM-1, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-ICAM-1 Antibody, hFc Tag with the EC50 of 7.3ng/ml determined by ELISA. See testing image for detail.
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Intercellular Adhesion Molecule 1 (ICAM1) (AA 28-485) protein (His tag)
ICAM1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Intercellular Adhesion Molecule 1 (ICAM1) (AA 28-480) protein (His tag)ICAM1 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Intercellular Adhesion Molecule 1 (ICAM1) protein (mFc Tag)ICAM1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Intercellular Adhesion Molecule 1 (ICAM1) (AA 28-480) (Active) protein (Fc Tag)ICAM1 宿主: 人 宿主: HEK-293 Cells Recombinant >98 % as determined by SDS-PAGE. Active
Intercellular Adhesion Molecule 1 (ICAM1) (AA 26-272) protein (His-IF2DI Tag)ICAM1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Intercellular Adhesion Molecule 1 (ICAM1) (AA 1-532) protein (GST tag)ICAM1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Intercellular Adhesion Molecule 1 (ICAM1) (Active) protein (His tag)ICAM1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE Active
Intercellular Adhesion Molecule 1 (ICAM1) (Active) protein (His tag,Fc Tag)ICAM1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE Active
Intercellular Adhesion Molecule 1 (ICAM1) (Active) protein (His tag)ICAM1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Intercellular Adhesion Molecule 1 (ICAM1) (AA 28-485) protein (His tag)Crystallography grade ICAM1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- 别名
- ICAM-1 (ICAM1 产品)
- 别名
- BB2 Protein, CD54 Protein, P3.58 Protein, Icam-1 Protein, Ly-47 Protein, MALA-2 Protein, ICAM Protein, ICAM-1 Protein, ICAM1 Protein, intercellular adhesion molecule 1 Protein, intercellular adhesion molecule-1 Protein, ICAM1 Protein, Icam1 Protein, ICAM-1 Protein
- 背景
- Intercellular adhesion molecule-1 (ICAM-1, CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and in animal models of atherosclerosis.
- 分子量
- 50.6 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.
- 途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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