ICAM1 蛋白
(Intercellular Adhesion Molecule 1 (ICAM1))
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| ICAM1 Protein (AA 28-480) (mFc Tag) | 人 | HEK-293 Cells |
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| ICAM1 Protein (AA 28-480) (His tag) | Cynomolgus | HEK-293 Cells |
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| ICAM1 Protein (AA 26-272) (His-IF2DI Tag) | 人 | 大肠杆菌（E. Coli） |
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| ICAM1 Protein (AA 28-485) (His tag) | 小鼠 | Mammalian Cells |
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| ICAM1 Protein (His-Fc tag) | 小鼠 | HEK-293 Cells |
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| ICAM1 Protein (His tag) | 小鼠 | HEK-293 Cells |
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| ICAM1 Protein (His tag) | 大鼠 | HEK-293 Cells |
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| ICAM1 Protein (AA 1-532) (GST tag) | 人 | 小麦胚 |
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| ICAM1 Protein (AA 28-485) (His tag) | 小鼠 | Mammalian Cells |
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| ICAM1 Protein (AA 28-482) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| ICAM1 Protein (AA 28-485) (mFc Tag) | 小鼠 | 人细胞 |
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| ICAM1 Protein (AA 28-480) (mFc Tag) | 人 | 人细胞 |
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| ICAM1 Protein (AA 28-480) (Fc Tag) | 猕猴 | 人细胞 |
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| ICAM1 Protein (AA 28-480) (His tag) | 猕猴 | 人细胞 |
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| ICAM1 Protein (Fc Tag,His tag) | 小鼠 | HEK-293 Cells |
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| ICAM1 Protein (AA 28-485, Extracellular Domain, N-Term) (Fc Tag) | 小鼠 | CHO Cells |
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| ICAM1 Protein (AA 28-480, Extracellular Domain, N-Term) (Fc Tag) | 人 | CHO Cells |
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| ICAM1 Protein (AA 25-476) (His tag) | 犬 | HEK-293 Cells |
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| ICAM1 Protein (AA 28-480) (hIgG-His-tag) | 人 | Baculovirus infected Insect Cells |
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| ICAM1 Protein (AA 28-485) (His tag) | 小鼠 | Baculovirus infected Insect Cells |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 小鼠
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- WB (Western Blotting: 有验证图片)
- CC (Cell Culture: 所列应用)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 96 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- CC (Cell Culture: 所列应用)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 96 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- CC (Cell Culture: 所列应用)
- 宿主
- 大鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 97 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- ELISA (ELISA: 所列应用)
- AcA (Activity Assay: 所列应用)
- 宿主
- 小鼠
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Protein
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % by SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 小鼠
- 宿主
- CHO Cells
- 蛋白类型
- Recombinant
- 纯度
- >98 % (SDS-PAGE)
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- CHO Cells
- 蛋白类型
- Recombinant
- 纯度
- >98 % (SDS-PAGE)
- 生物活性
- Active
Protein
- 宿主
- 犬
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 所列应用)
- AcA (Activity Assay: 所列应用)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 所列应用)
- AcA (Activity Assay: 所列应用)
- 宿主
- 小鼠
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
- 生物活性
- Active
Latest Publications for our ICAM1 蛋白
: "NPM1 upregulates the transcription of PD-L1 and suppresses T cell activity in triple-negative breast cancer." in: Nature communications, Vol. 11, Issue 1, pp. 1669, (2020) (PubMed).
: "PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways." in: Immunity, Vol. 51, Issue 6, pp. 1059-1073.e9, (2019) (PubMed).
: "LFA-1 Ligation by High-Density ICAM-1 Is Sufficient To Activate IFN-γ Release by Innate T Lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 8, pp. 2452-2461, (2018) (PubMed).
: "Supported Lipid Bilayer Technology for the Study of Cellular Interfaces." in: Current protocols in cell biology, Vol. 68, pp. 24.5.1-24.5.31, (2016) (PubMed).
: "Host ICAMs play a role in cell invasion by Mycobacterium tuberculosis and Plasmodium falciparum." in: Nature communications, Vol. 6, pp. 6049, (2015) (PubMed).
: "cDNA cloning reveals that the major group rhinovirus receptor on HeLa cells is intercellular adhesion molecule 1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 13, pp. 4907-11, (1989) (PubMed).
: "Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families." in: Cell, Vol. 52, Issue 6, pp. 925-33, (1988) (PubMed).
: "ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM." in: Nature, Vol. 331, Issue 6157, pp. 624-7, (1988) (PubMed).
: "PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways." in: Immunity, Vol. 51, Issue 6, pp. 1059-1073.e9, (2019) (PubMed).
: "LFA-1 Ligation by High-Density ICAM-1 Is Sufficient To Activate IFN-γ Release by Innate T Lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 8, pp. 2452-2461, (2018) (PubMed).
: "Supported Lipid Bilayer Technology for the Study of Cellular Interfaces." in: Current protocols in cell biology, Vol. 68, pp. 24.5.1-24.5.31, (2016) (PubMed).
: "Host ICAMs play a role in cell invasion by Mycobacterium tuberculosis and Plasmodium falciparum." in: Nature communications, Vol. 6, pp. 6049, (2015) (PubMed).
: "cDNA cloning reveals that the major group rhinovirus receptor on HeLa cells is intercellular adhesion molecule 1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 13, pp. 4907-11, (1989) (PubMed).
: "Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families." in: Cell, Vol. 52, Issue 6, pp. 925-33, (1988) (PubMed).
: "ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM." in: Nature, Vol. 331, Issue 6157, pp. 624-7, (1988) (PubMed).
Aliases for ICAM1 蛋白
intercellular adhesion molecule 1 (ICAM1) 蛋白intercellular adhesion molecule 1 (Icam1) 蛋白
intercellular adhesion molecule-1 (ICAM-1) 蛋白
BB2 蛋白
CD54 蛋白
ICAM 蛋白
Icam-1 蛋白
ICAM-1 蛋白
ICAM1 蛋白
Ly-47 蛋白
MALA-2 蛋白
P3.58 蛋白
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