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CSF2RA Protein (AA 23-320) (His tag)

CSF2RA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274781
发货至: 中国
  • 抗原 See all CSF2RA 蛋白
    CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))
    蛋白类型
    Recombinant
    产品特性
    AA 23-320
    宿主
    • 19
    • 4
    • 1
    资源
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This CSF2RA protein is labelled with His tag.
    原理
    Human GM-CSF R alpha Protein
    序列
    Glu23-Gly320
    产品特性
    Recombinant Human GM-CSF R alpha Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu23-Gly320.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human GM-CSF, No Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Human GM-CSF R alpha, His Tag with the EC50 of 1.0μg/ml determined by ELISA. The affinity constant of 0.79nM as determined in SPR assay (Biacore T200). See testing image for detail.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))
    别名
    GM-CSF R alpha (CSF2RA 产品)
    别名
    CD116 Protein, CDw116 Protein, CSF2R Protein, CSF2RAX Protein, CSF2RAY Protein, CSF2RX Protein, CSF2RY Protein, GM-CSF-R-alpha Protein, GMCSFR Protein, GMR Protein, SMDP4 Protein, Csfgmra Protein, GM-CSF-Ra Protein, GM-CSFR Protein, colony stimulating factor 2 receptor, alpha Protein, colony stimulating factor 2 receptor alpha subunit Protein, colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) Protein, CSF2RA Protein, Csf2ra Protein
    背景
    In the first trimester, the GM-CSF-R was found to be present on villous cytotrophoblast and all populations of extravillous trophoblast. Expression by villous syncytiotrophoblast was weak or absent, but this increased markedly by term. GM-CSF-R were also expressed by fetal Hofbauer cells within the mesenchyme of the chorionic villi and by uterine glandular epithelium and decidual macrophages within maternal decidua.
    分子量
    35.3 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
    途径
    JAK/STAT Signaling
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