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GFRAL Protein (AA 20-351) (His-Avi Tag,Biotin)

GFRAL 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274735
发货至: 中国
  • 抗原 See all GFRAL 蛋白
    GFRAL (GDNF Family Receptor alpha Like (GFRAL))
    蛋白类型
    Recombinant
    产品特性
    AA 20-351
    宿主
    • 6
    • 4
    • 1
    Cynomolgus
    资源
    • 7
    • 4
    HEK-293 Cells
    标记
    This GFRAL protein is labelled with His-Avi Tag,Biotin.
    原理
    Biotinylated Cynomolgus GFRAL/GFR alpha-like Protein
    序列
    Gln20-Glu351
    产品特性
    Recombinant Biotinylated Cynomolgus GFRAL/GFR alpha-like Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Gln20-Glu351.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Cynomolgus GDF15, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Cynomolgus GFRAL, His Tag with the EC50 of 76.3ng/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product GFRAL 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied as 0.22μm filtered solution in 20 mM PB, 400 mM NaCl ( pH 6.0).
    储存条件
    -80 °C
    储存方法
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    GFRAL (GDNF Family Receptor alpha Like (GFRAL))
    别名
    GFRAL (GFRAL 产品)
    别名
    RGD1565220 Protein, C6orf144 Protein, GRAL Protein, UNQ9356 Protein, bA360D14.1 Protein, AY457637 Protein, Gral Protein, GDNF family receptor alpha like Protein, Gfral Protein, GFRAL Protein
    背景
    GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses.
    分子量
    40.7 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
    NCBI登录号
    XP_015304775
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