GFRAL Protein (AA 20-351) (His-Avi Tag,Biotin)
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- 抗原 See all GFRAL 蛋白
- GFRAL (GDNF Family Receptor alpha Like (GFRAL))
- 蛋白类型
- Recombinant
- 产品特性
- AA 20-351
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宿主
- Cynomolgus
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资源
- HEK-293 Cells
- 标记
- This GFRAL protein is labelled with His-Avi Tag,Biotin.
- 原理
- Biotinylated Cynomolgus GFRAL/GFR alpha-like Protein
- 序列
- Gln20-Glu351
- 产品特性
- Recombinant Biotinylated Cynomolgus GFRAL/GFR alpha-like Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Gln20-Glu351.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus GDF15, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Cynomolgus GFRAL, His Tag with the EC50 of 76.3ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product GFRAL 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied as 0.22μm filtered solution in 20 mM PB, 400 mM NaCl ( pH 6.0).
- 储存条件
- -80 °C
- 储存方法
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- GFRAL (GDNF Family Receptor alpha Like (GFRAL))
- 别名
- GFRAL (GFRAL 产品)
- 别名
- RGD1565220 Protein, C6orf144 Protein, GRAL Protein, UNQ9356 Protein, bA360D14.1 Protein, AY457637 Protein, Gral Protein, GDNF family receptor alpha like Protein, Gfral Protein, GFRAL Protein
- 背景
- GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses.
- 分子量
- 40.7 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
- NCBI登录号
- XP_015304775
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