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FGF10 蛋白

FGF10 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90% as determined by Tris-Bis PAGE
产品编号 ABIN7274614
发货至: 中国
  • 抗原 See all FGF10 蛋白
    FGF10 (Fibroblast Growth Factor 10 (FGF10))
    蛋白类型
    Recombinant
    宿主
    • 11
    • 4
    • 4
    资源
    • 16
    • 2
    • 1
    大肠杆菌(E. Coli)
    序列
    Gln38-Ser208
    纯度
    > 90% as determined by Tris-Bis PAGE
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 0.299 nM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product FGF10 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in 20 mM Tris, 150 mM NaCl ( pH 8.0). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    4 °C,-80 °C
    储存方法
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    FGF10 (Fibroblast Growth Factor 10 (FGF10))
    别名
    FGF10 (FGF10 产品)
    别名
    fgf10 Protein, fgf-10 Protein, wu:fd11d03 Protein, zgc:109774 Protein, FGF10 Protein, AEY17 Protein, BB213776 Protein, Fgf-10 Protein, Gsfaey17 Protein, FGF-10 Protein, fibroblast growth factor 10a Protein, fibroblast growth factor 10 Protein, fgf10a Protein, FGF10 Protein, fgf10 Protein, Fgf10 Protein
    背景
    FGF-10, KGF2,Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling defects during development lead to neonatal lung disease. Lung diseases impact patients across the lifespan, from infants in the first minutes of life through the aged population. Congenital abnormalities of lung structure can cause lung disease at birth or make adults more susceptible to chronic disease.
    分子量
    19.3 kDa. The protein migrates to 25 kDa based on Tris-Bis PAGE result.
    UniProt
    O15520
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus
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