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FAM3D Protein (AA 26-224) (Fc Tag)

FAM3D 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274578
发货至: 中国
  • 抗原 See all FAM3D 蛋白
    FAM3D (Family with Sequence Similarity 3, Member D (FAM3D))
    蛋白类型
    Recombinant
    产品特性
    AA 26-224
    宿主
    • 5
    • 3
    资源
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This FAM3D protein is labelled with Fc Tag.
    原理
    Human FAM3D Protein
    序列
    Tyr26-Phe224
    产品特性
    Recombinant Human FAM3D Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Tyr26-Phe224.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product FAM3D 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    FAM3D (Family with Sequence Similarity 3, Member D (FAM3D))
    别名
    FAM3D (FAM3D 产品)
    别名
    Oit1 Protein, EF7 Protein, OIT1 Protein, 2310076N21Rik Protein, AV067083 Protein, EF-7 Protein, Fam3d Protein, family with sequence similarity 3, member D Protein, family with sequence similarity 3 member D Protein, oncoprotein induced transcript 1 Protein, Fam3d Protein, FAM3D Protein, Oit1 Protein
    背景
    The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (mouse Fam3D), is highly expressed in mouse gastrointestinal tract. Here, we demonstrate that deficiency in Fam3D is associated with impaired integrity of colonic mucosa, increased epithelial hyper-proliferation, reduced anti-microbial peptide production and increased sensitivity to chemically induced colitis associated with high incidence of cancer.
    分子量
    48.7 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
    UniProt
    Q96BQ1
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