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FAM3D Protein (AA 26-223) (hFc Tag)

This Recombinant FAM3D protein is expressed in HEK-293 Cells.
产品编号 ABIN7274580
发货至: 中国
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Quick Overview for FAM3D Protein (AA 26-223) (hFc Tag) (ABIN7274580)

抗原

See all FAM3D 蛋白
FAM3D (Family with Sequence Similarity 3, Member D (FAM3D))

蛋白类型

Recombinant

生物活性

Active

宿主

小鼠

资源

  • 2
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

纯度

> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
  • 产品特性

    AA 26-223

    标记

    This FAM3D protein is labelled with hFc Tag.

    原理

    Mouse FAM3D Protein

    序列

    Tyr26-Met223

    产品特性

    Recombinant Mouse FAM3D Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Tyr26-Met223.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 1 EU per μg by the LAL method.

    Biological Activity Comment

    Mouse FAM3D on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Mouse FAM3D is greater than 95% as determined by SEC-HPLC.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

    缓冲液

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    FAM3D (Family with Sequence Similarity 3, Member D (FAM3D))

    别名

    FAM3D

    背景

    The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (mouse Fam3D), is highly expressed in mouse gastrointestinal tract. Here, we demonstrate that deficiency in Fam3D is associated with impaired integrity of colonic mucosa, increased epithelial hyper-proliferation, reduced anti-microbial peptide production and increased sensitivity to chemically induced colitis associated with high incidence of cancer.

    分子量

    48.7 kDa. Due to glycosylation, the protein migrates to 52-58 kDa based on Bis-Tris PAGE result.

    UniProt

    P97805
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