FAM3D Protein (AA 26-223) (hFc Tag)
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北京 101111
Quick Overview for FAM3D Protein (AA 26-223) (hFc Tag) (ABIN7274580)
抗原
See all FAM3D 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 26-223
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标记
- This FAM3D protein is labelled with hFc Tag.
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原理
- Mouse FAM3D Protein
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序列
- Tyr26-Met223
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产品特性
- Recombinant Mouse FAM3D Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Tyr26-Met223.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Mouse FAM3D on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Mouse FAM3D is greater than 95% as determined by SEC-HPLC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- FAM3D (Family with Sequence Similarity 3, Member D (FAM3D))
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别名
- FAM3D
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背景
- The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (mouse Fam3D), is highly expressed in mouse gastrointestinal tract. Here, we demonstrate that deficiency in Fam3D is associated with impaired integrity of colonic mucosa, increased epithelial hyper-proliferation, reduced anti-microbial peptide production and increased sensitivity to chemically induced colitis associated with high incidence of cancer.
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分子量
- 48.7 kDa. Due to glycosylation, the protein migrates to 52-58 kDa based on Bis-Tris PAGE result.
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UniProt
- P97805
抗原
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