EPH Receptor A4 Protein (EPHA4) (AA 20-547) (His tag)
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- 抗原 See all EPH Receptor A4 (EPHA4) 蛋白
- EPH Receptor A4 (EPHA4)
- 蛋白类型
- Recombinant
- 产品特性
- AA 20-547
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This EPH Receptor A4 protein is labelled with His tag.
- 原理
- Human EPHA4 Protein
- 序列
- Val20-Thr547
- 产品特性
- Recombinant Human EPHA4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val20-Thr547.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product EPHA4 蛋白
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EPH Receptor A4 (EPHA4) (AA 20-547) protein (His tag)
EPHA4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
EPH Receptor A4 (EPHA4) (AA 586-986) (Active) protein (GST tag)EPHA4 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
EPH Receptor A4 (EPHA4) (AA 570-986) (Active) protein (His-GST)EPHA4 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
EPH Receptor A4 (EPHA4) (AA 887-986) protein (GST tag)EPHA4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
EPH Receptor A4 (EPHA4) (AA 1-105) protein (GST tag)EPHA4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
EPH Receptor A4 (EPHA4) (AA 1-986) protein (GST tag)EPHA4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
EPH Receptor A4 (EPHA4) (AA 570-986) (Active) protein (GST tag,His tag)EPHA4 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 99 % as determined by reducing SDS-PAGE. Active
EPH Receptor A4 (EPHA4) (Active) protein (His tag)EPHA4 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
EPH Receptor A4 (EPHA4) (Active) protein (Fc Tag)EPHA4 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- EPH Receptor A4 (EPHA4)
- 别名
- EPHA4 (EPHA4 产品)
- 别名
- HEK8 Protein, SEK Protein, TYRO1 Protein, RGD1560587 Protein, ephe Protein, EPHA4 Protein, Ci-Eph1 Protein, sek Protein, hek8 Protein, rtk1 Protein, tyr01 Protein, 2900005C20Rik Protein, AI385584 Protein, Cek8 Protein, Hek8 Protein, Sek Protein, Sek1 Protein, Tyro1 Protein, rb Protein, XEpha4 Protein, sek-1 Protein, epha4 Protein, pag Protein, EphA4 Protein, apha3 Protein, ek2 Protein, epha3 Protein, sb:cb246 Protein, zek2 Protein, zgc:109882 Protein, EPH receptor A4 Protein, Eph receptor A4 Protein, ephrin receptor epsilon Protein, EPH receptor A4 S homeolog Protein, EPH receptor A4 L homeolog Protein, eph receptor A4a Protein, EPHA4 Protein, Epha4 Protein, ephe Protein, epha4 Protein, epha4.S Protein, epha4.L Protein, epha4a Protein
- 背景
- The expression and activation of EphA4 in the various cell types in a knee joint was upregulated upon an intraarticular injury. To determine if EphA4 signaling plays a role in osteoarthritis, we determined whether deficient EphA4 expression (in EphA4 knockout mice) or upregulation of the EphA4 signaling (with the EfnA4-fc treatment) would alter cellular functions of synoviocytes and articular chondrocytes. In synoviocytes, deficient EphA4 expression enhanced, whereas activation of the EphA4 signaling reduced, expression and secretion of key inflammatory cytokines and matrix metalloproteases.
- 分子量
- 59.5 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
- 途径
- RTK signaling
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