Desmoglein 2 Protein (DSG2) (AA 50-609) (His tag)
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- 抗原 See all Desmoglein 2 (DSG2) 蛋白
- Desmoglein 2 (DSG2)
- 蛋白类型
- Recombinant
- 产品特性
- AA 50-609
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Desmoglein 2 protein is labelled with His tag.
- 原理
- Human DSG-2/Desmoglein-2 Protein
- 序列
- Ala50-Gly609
- 产品特性
- Recombinant Human DSG-2/Desmoglein-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala50-Gly609.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human DSG-2, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-DSG-2 Antibody, hFc Tag with the EC50 of 0.17ug/ml determined by ELISA. See testing image for detail.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Desmoglein 2 (DSG2)
- 别名
- DSG-2 (DSG2 产品)
- 别名
- DSG2 Protein, dsc Protein, dsga Protein, si:dkeyp-51f12.6 Protein, wu:fj23f02 Protein, ARVC10 Protein, ARVD10 Protein, CDHF5 Protein, CMD1BB Protein, HDGC Protein, AA408168 Protein, D18Ertd293e Protein, desmoglein 2 Protein, desmoglein 2, tandem duplicate 1 Protein, DSG2 Protein, dsg2.1 Protein, dsg2 Protein, Dsg2 Protein
- 背景
- Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions.
- 分子量
- 63.6 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Tris-Bis PAGE result.
- UniProt
- Q14126
- 途径
- Cell-Cell Junction Organization
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