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Desmoglein 2 Protein (DSG2) (AA 50-609) (His tag)

DSG2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274500
发货至: 中国
  • 抗原 See all Desmoglein 2 (DSG2) 蛋白
    Desmoglein 2 (DSG2)
    蛋白类型
    Recombinant
    产品特性
    AA 50-609
    宿主
    • 4
    • 4
    资源
    • 6
    • 1
    • 1
    HEK-293 Cells
    标记
    This Desmoglein 2 protein is labelled with His tag.
    原理
    Human DSG-2/Desmoglein-2 Protein
    序列
    Ala50-Gly609
    产品特性
    Recombinant Human DSG-2/Desmoglein-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala50-Gly609.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human DSG-2, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-DSG-2 Antibody, hFc Tag with the EC50 of 0.17ug/ml determined by ELISA. See testing image for detail.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Desmoglein 2 (DSG2)
    别名
    DSG-2 (DSG2 产品)
    别名
    DSG2 Protein, dsc Protein, dsga Protein, si:dkeyp-51f12.6 Protein, wu:fj23f02 Protein, ARVC10 Protein, ARVD10 Protein, CDHF5 Protein, CMD1BB Protein, HDGC Protein, AA408168 Protein, D18Ertd293e Protein, desmoglein 2 Protein, desmoglein 2, tandem duplicate 1 Protein, DSG2 Protein, dsg2.1 Protein, dsg2 Protein, Dsg2 Protein
    背景
    Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions.
    分子量
    63.6 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Tris-Bis PAGE result.
    UniProt
    Q14126
    途径
    Cell-Cell Junction Organization
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