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CD96 Protein (CD96) (AA 22-503) (mFc Tag)

CD96 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274270
发货至: 中国
  • 抗原 See all CD96 蛋白
    CD96
    蛋白类型
    Recombinant
    产品特性
    AA 22-503
    宿主
    • 17
    • 5
    • 1
    • 1
    • 1
    资源
    • 12
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This CD96 protein is labelled with mFc Tag.
    原理
    Human CD96/TACTILE Protein
    序列
    Val22-Met503
    产品特性
    Recombinant Human CD96/TACTILE Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Val22-Met503.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human CD96, mFc Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Human CD155, hFc Tag with the EC50 of 0.21μg/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product CD96 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    CD96
    别名
    CD96 (CD96 产品)
    别名
    1700109I12Rik Protein, Tactile Protein, TACTILE Protein, CD96 antigen Protein, CD96 molecule Protein, Cd96 Protein, CD96 Protein
    背景
    The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cell activity in mice, with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance. The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor, CD226, offers unique strategies for immuno-oncology drug development.
    分子量
    79.8 kDa. Due to glycosylation, the protein migrates to 120-160 kDa based on Tris-Bis PAGE result.
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