CD46 Protein (CD46) (AA 35-343) (His tag)
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- 抗原 See all CD46 蛋白
- CD46
- 蛋白类型
- Recombinant
- 产品特性
- AA 35-343
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD46 protein is labelled with His tag.
- 原理
- Human CD46 Protein
- 序列
- Cys35-Asp343
- 产品特性
- Recombinant Human CD46 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys35-Asp343.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human CD46, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-CD46 Antibody, hFc Tag with the EC50 of 25.3ng/ml determined by ELISA. See testing image for detail.
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CD46 (CD46) (AA 35-329) protein (His tag)
CD46 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD46 (CD46) (AA 45-344) protein (His tag)CD46 宿主: 犬 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD46 (CD46) (AA 35-313) protein (His tag)CD46 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
CD46 (CD46) (AA 1-384) protein (GST tag)CD46 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD46 (CD46) (AA 36-135) protein (GST tag)CD46 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD46 (CD46) (AA 45-329) protein (His tag)Crystallography grade CD46 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
CD46 (CD46) (AA 45-365) protein (rho-1D4 tag)Crystallography grade CD46 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CD46
- 别名
- CD46 (CD46 产品)
- 别名
- AHUS2 Protein, MCP Protein, MIC10 Protein, TLX Protein, TRA2.10 Protein, Mcp Protein, CD46 Protein, CD46 molecule Protein, CD46 antigen, complement regulatory protein Protein, CD46 molecule, complement regulatory protein Protein, membrane cofactor protein-like Protein, CD46 Protein, Cd46 Protein, LOC100341359 Protein, LOC103789310 Protein
- 背景
- CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'.
- 分子量
- 35.4 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
- 途径
- Regulation of Actin Filament Polymerization
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