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CD46 Protein (CD46) (AA 45-344) (His tag)

CD46 宿主: 犬 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274176
发货至: 中国
  • 抗原 See all CD46 蛋白
    CD46
    蛋白类型
    Recombinant
    产品特性
    AA 45-344
    宿主
    • 13
    • 4
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    资源
    • 7
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    HEK-293 Cells
    标记
    This CD46 protein is labelled with His tag.
    原理
    Canine CD46 Protein
    序列
    Cys45-Gly344
    产品特性
    Recombinant Canine CD46 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys45-Gly344.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product CD46 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    CD46
    别名
    CD46 (CD46 产品)
    别名
    AHUS2 Protein, MCP Protein, MIC10 Protein, TLX Protein, TRA2.10 Protein, Mcp Protein, CD46 Protein, CD46 molecule Protein, CD46 antigen, complement regulatory protein Protein, CD46 molecule, complement regulatory protein Protein, membrane cofactor protein-like Protein, CD46 Protein, Cd46 Protein, LOC100341359 Protein, LOC103789310 Protein
    背景
    CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'.
    分子量
    34.11 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
    UniProt
    A0A8C0YZN5
    途径
    Regulation of Actin Filament Polymerization
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