CD86 Protein (CD86) (AA 26-240) (His tag)
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- 抗原 See all CD86 蛋白
- CD86
- 蛋白类型
- Recombinant
- 产品特性
- AA 26-240
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宿主
- Cynomolgus
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资源
- HEK-293 Cells
- 标记
- This CD86 protein is labelled with His tag.
- 原理
- Cynomolgus B7-2/CD86 Protein
- 序列
- Tyr26-His240
- 产品特性
- Recombinant Cynomolgus B7-2/CD86 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr26-His240.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.102 μM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product CD86 蛋白
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CD86 (CD86) (AA 26-247) protein (Fc Tag)
CD86 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD86 (CD86) protein (His-Avi Tag)CD86 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
CD86 (CD86) (AA 19-240) protein (His tag)HPLC verified CD86 宿主: Cynomolgus, 猕猴 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
CD86 (CD86) (AA 26-247) (Active) protein (Fc Tag)CD86 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD86 (CD86) protein (His-Avi Tag,Biotin)CD86 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
CD86 (CD86) (AA 24-246) protein (His-DYKDDDDK-Strep II Tag)CD86 宿主: 人 宿主: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
CD86 (CD86) (AA 24-245) (Active) protein (Fc Tag)CD86 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD86 (CD86) (AA 26-247) (Active) protein (His tag)CD86 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD86 (CD86) (AA 26-247) (Active) protein (Fc Tag,AVI tag,Biotin)CD86 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD86 (CD86) protein (His tag)CD86 宿主: 猕猴 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CD86
- 别名
- B7-2 (CD86 产品)
- 别名
- B7-2 Protein, B7.2 Protein, B70 Protein, CD28LG2 Protein, LAB72 Protein, B7 Protein, CLS1 Protein, Cd28l2 Protein, ETC-1 Protein, Ly-58 Protein, Ly58 Protein, MB7 Protein, MB7-2 Protein, TS/A-2 Protein, CD86 molecule Protein, CD86 antigen Protein, integrin subunit alpha 2b Protein, CD86 Protein, Cd86 Protein, Itga2b Protein
- 背景
- B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively.
- 分子量
- 26.4 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
- UniProt
- G7NXR4
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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