CD22 Protein (His tag,Biotin)
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- 抗原 See all CD22 蛋白
- CD22 (CD22 Molecule (CD22))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 人细胞
- 标记
- This CD22 protein is labelled with His tag,Biotin.
- 原理
- Recombinant Human B-cell Receptor CD22/Siglec-2/CD22 (C-6His) Biotinylated
- 序列
- Asp20-Arg687
- 产品特性
- Biotinylated Recombinant Human B-cell Receptor CD22 is produced by our Mammalian expression system and the target gene encoding Asp20-Arg687 is expressed with a 6His, Avi tag at the C-terminus.
- 纯度
- >95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Loaded Biotinylated Human Siglec-2-His-Avi(Cat#CY36) on HIS1K Biosensor, can bind Anti-Human Siglec-2 mAb-Fc(Cat#NC013) with an affinity constant of 0.16 nM as determined in BLI assay.
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- Discover our top product CD22 蛋白
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CD22 Molecule (CD22) (AA 20-687) protein (Fc Tag)
CD22 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD22 Molecule (CD22) (AA 20-687) protein (His tag)CD22 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD22 Molecule (CD22) (AA 20-687) protein (His-Avi Tag,Biotin)CD22 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD22 Molecule (CD22) (AA 22-702) protein (His tag)CD22 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD22 Molecule (CD22) (AA 20-686) protein (His tag)CD22 宿主: 猕猴 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD22 Molecule (CD22) protein (Fc-His Tag)CD22 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
CD22 Molecule (CD22) protein (Fc Tag)CD22 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
CD22 Molecule (CD22) (AA 20-687) protein (FITC,Fc Tag)CD22 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD22 Molecule (CD22) (AA 707-847) protein (His tag)Crystallography grade CD22 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
CD22 Molecule (CD22) (AA 722-862) protein (His tag)Crystallography grade CD22 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 说明
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110-130 kDa
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CD22 (CD22 Molecule (CD22))
- 别名
- CD22 (CD22 产品)
- 别名
- A530093D23 Protein, Lyb-8 Protein, Lyb8 Protein, SIGLEC-2 Protein, SIGLEC2 Protein, siglec-2 Protein, CD22 antigen Protein, CD22 molecule Protein, Cd22 Protein, CD22 Protein
- 背景
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Background: Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Human Siglec-2, also known as B-cell antigen CD22 or B-lymphocyte cell adhesion molecule (BL-CAM), is a B-cell restricted glycoprotein that is expressed in the cytoplasm of progenitor B and pre-B cells and on the surface of mature B cells. Two distinct human Siglec-2/CD22 cDNAs that arise from differential RNA processing of the same gene have been isolated. Siglec-2/CD22 is an adhesion molecule that preferentially binds alpha 2,6- linked sialic acid on the same (cis) or adjacent (trans) cells. Interaction of CD22 with trans ligands on opposing cells was found to be favored over the binding of ligands in cis.
Synonym: B-cell receptor CD22, BL-CAM, B-lymphocyte cell adhesion molecule, CD22 antigenMGC130020, CD22 Molecule, CD22, sialic acid binding Ig-like lectin 2, Siglec-2, SIGLEC2FLJ22814, T-cell surface antigen Leu-14
- 分子量
- 78 kDa
- UniProt
- P20273
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