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WIF1 Protein (His tag)

WIF1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 93 % as determined by SDS-PAGE
产品编号 ABIN7320086
发货至: 中国
  • 抗原 See all WIF1 蛋白
    WIF1 (WNT Inhibitory Factor 1 (WIF1))
    蛋白类型
    Recombinant
    宿主
    • 8
    • 2
    • 1
    • 1
    小鼠
    资源
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This WIF1 protein is labelled with His tag.
    原理
    Recombinant Mouse Wnt Inhibitory Factor 1/WIF1 Protein (His Tag)
    序列
    Met1-Trp379
    产品特性
    A DNA sequence encoding the mouse WIF1 (Q9WUA1) (Met1-Trp379) was expressed with a C-terminal polyhistidine tag.
    纯度
    > 93 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product WIF1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    WIF1 (WNT Inhibitory Factor 1 (WIF1))
    别名
    Wnt Inhibitory Factor 1/WIF1 (WIF1 产品)
    别名
    shf Protein, GB10372 Protein, wif-1 Protein, WIF1 Protein, WIF-1 Protein, AW107799 Protein, zgc:110507 Protein, protein shifted Protein, wnt inhibitory factor 1 Protein, WNT inhibitory factor 1 Protein, Wnt inhibitory factor 1 Protein, WNT inhibitory factor 1 S homeolog Protein, LOC552805 Protein, CpipJ_CPIJ003761 Protein, wif1 Protein, WIF1 Protein, Wif1 Protein, LOC100511326 Protein, wif1.S Protein
    背景

    Background: WIF1, also known as WIF-1 and wnt inhibitory factor 1, is a secreted protein which binds WNT proteins and inhibits their activities. It contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. WNT proteins are extracellular signaling molecules involved in the control of embryonic development. WIF1 may be involved in mesoderm segmentation and can be detected in fish, amphibia and mammals. WIF-1 is a recurrent target in human salivary gland oncogenesis. Downregulation of WIF1 takes part in the development and progression of pleomorphic adenomas. WIF1 also is a tumor suppressor, and has been found to be epigenetically silenced in various cancers, specifically in nonfunctioning pituitary tumors. WIF1 are expected to have molecular function (protein tyrosine kinase activity) and to localize in various compartments (extracellular space, extracellular region).

    Synonym: AW107799,WIF-1

    分子量
    39.8 kDa
    UniProt
    Q9WUA1
    途径
    WNT signaling, Positive Regulation of fat Cell Differentiation
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