Vitamin D Receptor Protein (VDR) (His tag)
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- 抗原 See all Vitamin D Receptor (VDR) 蛋白
- Vitamin D Receptor (VDR)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This Vitamin D Receptor protein is labelled with His tag.
- 原理
- Recombinant Human VDR/NR1I1 Protein (His Tag)
- 序列
- Met 1-Ser 427
- 产品特性
- A DNA sequence encoding the human VDR (P11473) (Met 1-Ser 427) was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 88 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product VDR 蛋白
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Vitamin D Receptor (VDR) (AA 1-427) protein (GST tag)
VDR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Vitamin D Receptor (VDR) (AA 318-427) protein (GST tag)VDR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Vitamin D Receptor (VDR) protein (His tag)VDR 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 86 % as determined by SDS-PAGE
Vitamin D Receptor (VDR) (AA 1-427) protein (Strep Tag)Crystallography grade VDR 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Vitamin D Receptor (VDR) (AA 272-427) (Active) protein (His tag)VDR 宿主: 人 宿主: 大肠杆菌（E. Coli） > 90 % AcA, CC Active
Vitamin D Receptor (VDR) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)VDR 宿主: 化学剂 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Vitamin D Receptor (VDR) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)VDR 宿主: 化学剂 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Vitamin D Receptor (VDR)
- 别名
- VDR/NR1I1 (VDR 产品)
- 别名
- vdrbeta Protein, vdr0 Protein, LOC100136219 Protein, NR1I1-B Protein, gb:dq017633 Protein, vdr-b Protein, Ci-VDR-b Protein, VDR Protein, LOC100221284 Protein, vdr-A Protein, xVDR Protein, Nr1i1 Protein, vdr Protein, NR1I1 Protein, PPP1R163 Protein, vitamin D (1,25- dihydroxyvitamin D3) receptor Protein, vitamin D receptor Protein, vitamin D3 receptor A Protein, vitamin D receptor b Protein, nuclear receptor VDR-b Protein, vitamin D (1,25- dihydroxyvitamin D3) receptor L homeolog Protein, vitamin D (1,25-dihydroxyvitamin D3) receptor Protein, vitamin D receptor a Protein, vdr Protein, vdr0 Protein, VDR Protein, LOC100136219 Protein, vdrb Protein, vdr-b Protein, vdr.L Protein, Vdr Protein, vdra Protein
- 物质类
- Chemical
- 背景
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Background: VDR (vitamin D(1,25- dihydroxyvitamin D3)receptor), also known as NR1I1, belongs to the NR1I family, NR1 subfamily. It is composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain. Vitamin D receptors (VDRs) are members of the NR1I family, which also includes pregnane X (PXR) and constitutive androstane (CAR) receptors, that form heterodimers with members of the retinoid X receptor family. VDRs repress expression of 1alpha-hydroxylase (the proximal activator of 1,25(OH)2D3) and induce expression of the 1,25(OH)2D3 inactivating enzyme CYP24. Also, it has recently been identified as an additional bile acid receptor alongside FXR and may function to protect gut against the toxic and carcinogenic effects of these endobiotics. VDR is expressed in the intestine, thyroid and kidney and has a vital role in calcium homeostasis. It is the nuclear hormone receptor, also called transcription factor that mediates the action of vitamin D3. Inherited mutations in the VDR gene leads to rickets.
Synonym: NR1I1,PPP1R163
- 分子量
- 50 KDa
- UniProt
- P11473
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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