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UBE2D1 Protein (His tag)

UBE2D1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7198578
发货至: 中国
  • 抗原 See all UBE2D1 蛋白
    UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
    蛋白类型
    Recombinant
    宿主
    • 9
    • 1
    • 1
    资源
    • 5
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This UBE2D1 protein is labelled with His tag.
    原理
    Recombinant Human UBE2D1 Protein (His Tag)
    序列
    Ala 2-Met 147
    产品特性
    A DNA sequence encoding the human UBE2D1 (P51668) (Ala 2-Met 147) was expressed, with a polyhistide tag at the N-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product UBE2D1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 25 mM Tris, 100 mM NaCl, 20 % glycerol, 0.05 % Tween
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
    别名
    UBE2D1 (UBE2D1 产品)
    别名
    E2(17)KB1 Protein, SFT Protein, UBC4/5 Protein, UBCH5 Protein, UBCH5A Protein, ube2d1 Protein, wu:fc16h06 Protein, zgc:73096 Protein, e2(17)kb1 Protein, sft Protein, ubc4/5 Protein, ubch5 Protein, ubch5a Protein, ubiquitin conjugating enzyme E2 D1 Protein, ubiquitin-conjugating enzyme E2D 1 Protein, ubiquitin-conjugating enzyme E2D 1b Protein, ubiquitin conjugating enzyme E2 D1 S homeolog Protein, UBE2D1 Protein, Ube2d1 Protein, ube2d1b Protein, ube2d1.S Protein, ube2d1 Protein
    背景

    Background: Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis, as previously published for SFT. Moreover, a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant KRAS to kill cancer cells.

    Synonym: Ubiquitin-conjugating enzyme E2 D1,Stimulator of Fe transport,SFT,UBC4/5 homolog,UbcH5,Ubiquitin carrier protein D1,Ubiquitin-conjugating enzyme E2(17)KB 1,Ubiquitin-conjugating enzyme E2-17 kDa 1,Ubiquitin-protein ligase D1,SFT, UBC5A, UBCH5, UBCH5A

    分子量
    18.3 kDa
    UniProt
    P51668
    途径
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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