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CD137 Protein (Fc Tag)

TNFRSF9 宿主: Cynomolgus 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7320979
发货至: 中国
  • 抗原 See all CD137 (TNFRSF9) 蛋白
    CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
    蛋白类型
    Recombinant
    宿主
    • 39
    • 14
    • 4
    • 4
    • 1
    • 1
    • 1
    Cynomolgus
    资源
    • 35
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    人细胞
    标记
    This CD137 protein is labelled with Fc Tag.
    原理
    Recombinant Cynomolgus 4-1BB/TNFRSF9/CD137 Protein (Fc Tag)
    序列
    Leu24-Gln186
    产品特性
    Recombinant Cynomolgus 4-1BB ligand receptor is produced by our Mammalian expression system and the target gene encoding Leu24-Gln186 is expressed with a Fc tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product TNFRSF9 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
    别名
    4-1BB/TNFRSF9/CD137 (TNFRSF9 产品)
    别名
    TNFRSF9 Protein, zgc:136557 Protein, 4-1BB Protein, CD137 Protein, CDw137 Protein, ILA Protein, A930040I11Rik Protein, AA408498 Protein, AI325004 Protein, Cd137 Protein, Ly63 Protein, tumor necrosis factor receptor superfamily member 9 Protein, TNF receptor superfamily member 9 Protein, tumor necrosis factor receptor superfamily, member 9a Protein, tumor necrosis factor receptor superfamily, member 9 Protein, TNFRSF9 Protein, tnfrsf9a Protein, Tnfrsf9 Protein
    背景

    Background: Tumor necrosis factor receptor superfamily member 9(TNFRSF9), also known as CD137 and 4-1BB, is an inducible T cell surface protein belonging to the tumor necrosis factor receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60 % amino acid sequence identity. CD137 is expressed by mesenchymal cells, including endothelial cells, chondrocytes, and cells of the central nervous system. CD137 is also broadly expressed by cells of the human immune system, is broadly expressed by cells of the human immune system, including activated CD8+ and CD4+ T cells, activated natural killer (NK) cells, follicular dendritic cells (FDCs) and monocytes. CD137 has diverse roles in the immune response, the one key function is to promote the survival of both T cells and dendritic cells by binding the cognate ligand CD137L (4-1BBL).

    Synonym: CD137, ILA, TNFRSF9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA

    分子量
    44.4 kDa
    UniProt
    A9YYE7
    途径
    Cancer Immune Checkpoints
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