TNFRSF6B Protein (Fc Tag)
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- 抗原 See all TNFRSF6B 蛋白
- TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This TNFRSF6B protein is labelled with Fc Tag.
- 原理
- Recombinant Human DCR3/TNFRSF6B Protein (Fc Tag)(Active)
- 序列
- Met 1-His300
- 产品特性
- A DNA sequence encoding the human DCR3 (O95407)(Met1-His300) was expressed with the Fc region of human IgG1 at the C-terminus.
- 纯度
- > 85 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to inhibit Fas Ligand induced apoptosis of Jurkat human acute T cell leukemia cells.The ED50 for this effect is typically 0.01-0.05 μg/mL in the presence of 20 ng/mL recombinant human Fas Ligand.
- Top Product
- Discover our top product TNFRSF6B 蛋白
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Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B) (AA 30-300) protein (His-DYKDDDDK-Strep II Tag)
TNFRSF6B 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, ELISA, WB, PI
Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B) (AA 32-141) protein (GST tag)TNFRSF6B 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B) (AA 30-300) protein (His tag)Crystallography grade TNFRSF6B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B) (AA 30-300) protein (Fc Tag)TNFRSF6B 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B) (AA 30-300) protein (His tag)TNFRSF6B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % by SDS - PAGE SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 100 mM Glycine, 10 mM NaCl, pH 7.0.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))
- 别名
- DCR3/TNFRSF6B (TNFRSF6B 产品)
- 别名
- DCR3 Protein, DJ583P15.1.1 Protein, M68 Protein, M68E Protein, TR6 Protein, dcr3 Protein, m68 Protein, tr6 Protein, TNF receptor superfamily member 6b Protein, tumor necrosis factor receptor superfamily, member 11b Protein, regulator of telomere elongation helicase 1 Protein, TNF receptor superfamily member 6b L homeolog Protein, TNFRSF6B Protein, tnfrsf11b Protein, RTEL1 Protein, tnfrsf6b Protein, tnfrsf6b.L Protein
- 背景
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Background: Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) also known as DcR3(Decoy Receptor 3) and M68 is the tumor necrosis factor receptor superfamily. DcR3/TNFRSF6B belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. DcR3/TNFRSF6B is detected in fetal lung, brain and liver. DcR3/TNFRSF6B is also detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. This protein is highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.
Synonym: DCR3,DJ583P15.1.1,M68,M68E,TNFRSF6B,TR6
- 分子量
- 56.4 kDa
- UniProt
- O95407
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