TNFRSF6B Protein (AA 24-300) (Fc Tag)
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- 抗原 See all TNFRSF6B 蛋白
- TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-300
- 宿主
- 人
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资源
- CHO Cells
- 标记
- This TNFRSF6B protein is labelled with Fc Tag.
- 原理
- DcR3 (human):Fc (human) (rec.)
- 特异性
- The extracellular domain of human DcR3 (aa 24-300) is fused to the N-terminus of the Fc region of human IgG1.
- 产品特性
- Protein. The extracellular domain of human DcR3 (aa 24-300) is fused to the N-terminus of the Fc region of human IgG1. Source: CHO cells. Endotoxin content: <0.06EU/μg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >98 % (SDS-PAGE). Decoy receptor 3 (DcR3, TNFRSF6B, M68) is a member of the TNF receptor superfamily. DcR3 shares sequence identity with OPG (31 %), TNF-RII (29 %) and Fas (17 %) and is expressed in a variety of different tissues and at high levels in many malignant tumors. Ligands of DcR3 include Fas ligand, homologous to lymphotoxin showing inducible expression and competing with HSV glycoprotein D for herpes virus entry mediator (a receptor expressed by T lymphocytes), TNF-like molecule 1A and heparan sulfate proteoglycans. DcR3 modulates the function of T cells, dendritic cells and macrophages. DcR3/Fc fusion proteins can bind to human and mouse B cells and suppress the activation of B cells.
- 纯度
- >98 % (SDS-PAGE)
- 内毒素水平
- <0.06EU/μg protein (LAL test, Lonza).
- Top Product
- Discover our top product TNFRSF6B 蛋白
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Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B) (AA 30-300) protein (His-DYKDDDDK-Strep II Tag)
TNFRSF6B 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, ELISA, WB, PI
Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B) (AA 32-141) protein (GST tag)TNFRSF6B 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B) (AA 30-300) protein (His tag)Crystallography grade TNFRSF6B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B) (AA 30-300) protein (Fc Tag)TNFRSF6B 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B) (AA 30-300) protein (His tag)TNFRSF6B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % by SDS - PAGE SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized from 0.2μm-filtered solution in PBS.
- 注意事项
- Avoid freeze/thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- 抗原
- TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))
- 别名
- DcR3 (TNFRSF6B 产品)
- 别名
- DCR3 Protein, DJ583P15.1.1 Protein, M68 Protein, M68E Protein, TR6 Protein, dcr3 Protein, m68 Protein, tr6 Protein, TNF receptor superfamily member 6b Protein, tumor necrosis factor receptor superfamily, member 11b Protein, regulator of telomere elongation helicase 1 Protein, TNF receptor superfamily member 6b L homeolog Protein, TNFRSF6B Protein, tnfrsf11b Protein, RTEL1 Protein, tnfrsf6b Protein, tnfrsf6b.L Protein
- 背景
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Alternate Names/Synonyms: Decoy Receptor 3, Tumor Necrosis Factor Receptor Superfamily Member 6B, TNFRSF6B, M68
Product Description: Decoy receptor 3 (DcR3, TNFRSF6B, M68) is a member of the TNF receptor superfamily. DcR3 shares sequence identity with OPG (31 % ), TNF-RII (29 %) and Fas (17 %) and is expressed in a variety of different tissues and at high levels in many malignant tumors. Ligands of DcR3 include Fas ligand, homologous to lymphotoxin showing inducible expression and competing with HSV glycoprotein D for herpes virus entry mediator (a receptor expressed by T lymphocytes), TNF-like molecule 1A and heparan sulfate proteoglycans. DcR3 modulates the function of T cells, dendritic cells and macrophages. DcR3/Fc fusion proteins can bind to human and mouse B cells and suppress the activation of B cells.
- UniProt
- O95407
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