Tryptophan Hydroxylase 1 Protein (TPH1) (His tag)
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- 抗原 See all Tryptophan Hydroxylase 1 (TPH1) 蛋白
- Tryptophan Hydroxylase 1 (TPH1)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Tryptophan Hydroxylase 1 protein is labelled with His tag.
- 原理
- Recombinant Human Tryptophan Hydroxylase 1/TPH1 Protein (His Tag)
- 序列
- Ile 2-Ile 444
- 产品特性
- A DNA sequence encoding the human TPH1 (P17752-1) (Ile 2-Ile 444) was expressed, with a polyhistide tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product TPH1 蛋白
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Tryptophan Hydroxylase 1 (TPH1) (AA 105-420) protein (His tag)
TPH1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Tryptophan Hydroxylase 1 (TPH1) (AA 1-444) protein (GST tag)TPH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Tryptophan Hydroxylase 1 (TPH1) (AA 1-117) protein (GST tag)TPH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Tryptophan Hydroxylase 1 (TPH1) (AA 1-444) protein (Strep Tag)Crystallography grade TPH1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Tryptophan Hydroxylase 1 (TPH1) (AA 1-447) protein (Strep Tag)Crystallography grade TPH1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Tryptophan Hydroxylase 1 (TPH1) protein (Myc-DYKDDDDK Tag)TPH1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 200 mM NaCl, 10 % glycerol, pH 8.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Tryptophan Hydroxylase 1 (TPH1)
- 别名
- Tryptophan Hydroxylase 1/TPH1 (TPH1 产品)
- 别名
- TPRH Protein, TRPH Protein, tph Protein, tph1 Protein, tphD1 Protein, tph2 Protein, tph1l Protein, tphD2 Protein, Tph Protein, TPH Protein, SERGEF Protein, LOC100229598 Protein, tryptophan hydroxylase 1 Protein, tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a Protein, TryPtophan Hydroxylase Protein, tryptophan hydroxylase 1b Protein, tryptophan hydroxylase 1 L homeolog Protein, tryptophan 5-hydroxylase 1 Protein, TPH1 Protein, tph1a Protein, tph-1 Protein, tph1b Protein, Tph1 Protein, tph1.L Protein, LOAG_02149 Protein, Tsp_05203 Protein
- 背景
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Background: Tryptophan 5-hydroxylase 1, also known as Tryptophan 5-monooxygenase 1, Tryptophan hydroxylase 1, TPH1, TPH and TPRH, is an enzyme which belongs to the biopterin-dependent aromatic amino acid hydroxylase family. TPH1 contains one ACT domain. Tryptophan hydroxylase catalyzes the biopterin-dependent monooxygenation of tryptophan to 5-hydroxytryptophan (5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. It is the rate-limiting enzyme in the biosynthesis of serotonin. It is the rate-limiting enzyme in the biosynthesis of serotonin. TPH1 expression is limited to a few specialized tissues: raphe neurons, pinealocytes, mast cells, mononuclear leukocytes, beta-cells of the islets of Langerhans, and intestinal and pancreatic enterochromaffin cells.The tryptophan hydroxylase 1 (TPH1) gene is also reported to be associated with suicidal behavior. Polymorphisms of TPH1 may assist in identifying a subgroup of mood disorder patients that is at higher risk for suicidal behavior.
Synonym: TPRH;TRPH
- 分子量
- 52.7 kDa
- 途径
- Feeding Behaviour
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