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TPP1 Protein (His tag)

TPP1 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319430
发货至: 中国
  • 抗原 See all TPP1 蛋白
    TPP1 (Tripeptidyl Peptidase I (TPP1))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    人细胞
    标记
    This TPP1 protein is labelled with His tag.
    原理
    Recombinant Human TPP1/CLN2 Protein (His Tag)
    序列
    Ser20-Pro563
    产品特性
    Recombinant Human TPP1 is produced by our Mammalian expression system and the target gene encoding Ser20-Pro563 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product TPP1 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM GaCl2,10 % Glycerol, pH 7.5.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    TPP1 (Tripeptidyl Peptidase I (TPP1))
    别名
    TPP1/CLN2 (TPP1 产品)
    别名
    cln2 Protein, fa01b09 Protein, im:7149243 Protein, wu:fa01b09 Protein, CLN2 Protein, LPIC Protein, TPP-1 Protein, TPP-I Protein, Cln2 Protein, tripeptidyl peptidase I Protein, tripeptidyl-peptidase 1 Protein, tripeptidyl peptidase 1 Protein, tpp1 Protein, NAEGRDRAFT_78259 Protein, MCYG_00184 Protein, MGYG_05881 Protein, MGYG_00757 Protein, TPP1 Protein, Tpp1 Protein
    背景

    Background: Tripeptidyl-Peptidase 1 (TPP1) belongs to the peptidase S53 family. TPP1 is detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues. TPP1 is lysosomal serine protease with tripeptidyl-peptidase I activity. TPP1 may act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. TPP1 requires substrates with an unsubstituted N-terminus. TPP1 mutations have also been shown to cause neuronal ceroid lipofuscinosis type 2 (CLN2).

    Synonym: Tripeptidyl-Peptidase 1, TPP-1, Cell Growth-Inhibiting Gene 1 Protein, Lysosomal Pepstatin-Insensitive Protease, LPIC, Tripeptidyl Aminopeptidase, TPP1, CLN2,GIG1,LPIC,SCAR7,TPP-1

    分子量
    60.35 kDa
    UniProt
    O14773
    途径
    Cell Division Cycle, ER-Nucleus Signaling
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