电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

TRIM5 Protein (His tag)

TRIM5 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319116
发货至: 中国
  • 抗原 See all TRIM5 蛋白
    TRIM5 (Tripartite Motif Containing 5 (TRIM5))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 14
    • 4
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This TRIM5 protein is labelled with His tag.
    原理
    Recombinant Human TRIM5/RNF88 Protein (His Tag)
    序列
    Met 1-Gln248
    产品特性
    Recombinant Human Tripartite motif-containing protein 5 is produced by our E.coli expression system and the target gene encoding Met1-Gln248 is expressed with a 6His tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product TRIM5 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    TRIM5 (Tripartite Motif Containing 5 (TRIM5))
    别名
    TRIM5/RNF88 (TRIM5 产品)
    别名
    TRIM5 Protein, RNF88 Protein, TRIM5alpha Protein, EG667823 Protein, Gm8833 Protein, RGD1304579 Protein, tripartite motif containing 5 Protein, tripartite motif-containing 5 Protein, TRIM5 Protein, Trim5 Protein
    背景

    Background: Tripartite motif-containing Motif 5 is a protein that in humans is encoded by the TRIM5 gene.It is a 493 amino acids protein that belongs to the TRIM/RBCC family.It contains 1 B box-type zinc finger, 1 B30.2/SPRY domain and 1 RING-type zinc finger. TRIM5 present in the cytoplasm recognizes motifs within the capsid proteins and interferes with the uncoating process, therefore preventing successful reverse transcription and transport to the nucleus of the viral genome. The exact mechanism of action has not been shown conclusively, but capsid protein from restricted viruses is removed by proteasome-dependent degradation

    Synonym: Tripartite motif-containing protein 5,RING finger protein 88,TRIM5,RNF88

    分子量
    30.8 kDa
    UniProt
    Q9C035
    途径
    Activation of Innate immune Response
You are here: