TRIM5 Protein (AA 1-248) (His tag)
-
- 抗原 See all TRIM5 蛋白
- TRIM5 (Tripartite Motif Containing 5 (TRIM5))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-248
-
宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 标记
- This TRIM5 protein is labelled with His tag.
- 原理
- Recombinant Human Tripartite Motif-Containing Protein 5/TRIM5/RNF88 (N-6His)
- 序列
- MGSSHHHHHH SSGLVPRGSH MASGILVNVK EEVTCPICLE LLTQPLSLDC GHSFCQACLT ANHKKSMLDK GESSCPVCRI SYQPENIRPN RHVANIVEKL REVKLSPEGQ KVDHCARHGE KLLLFCQEDG KVICWLCERS QEHRGHHTFL TEEVAREYQV KLQAALEMLR QKQQEAEELE ADIREEKASW KTQIQYDKTN VLADFEQLRD ILDWEESNEL QNLEKEEEDI LKSLTNSETE MVQQTQSLRE LISDLEHRLQ GSVMELLQ
- 产品特性
- Recombinant Human TRIM5 is produced by our E. coli expression system. The target protein is expressed with sequence (AA 1-248) of Human TRIM5 fused with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product TRIM5 蛋白
-
Tripartite Motif Containing 5 (TRIM5) (AA 309-418) protein (GST tag)
TRIM5 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Tripartite Motif Containing 5 (TRIM5) (AA 1-347) protein (GST tag)TRIM5 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Tripartite Motif Containing 5 (TRIM5) proteinTRIM5 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant ELISA, WB, SDS, IP
-
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 溶解方式
-
It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
-
Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
-
- 抗原
- TRIM5 (Tripartite Motif Containing 5 (TRIM5))
- 别名
- Tripartite Motif-Containing Protein 5 (TRIM5 产品)
- 别名
- TRIM5 Protein, RNF88 Protein, TRIM5alpha Protein, EG667823 Protein, Gm8833 Protein, RGD1304579 Protein, tripartite motif containing 5 Protein, tripartite motif-containing 5 Protein, TRIM5 Protein, Trim5 Protein
- 背景
- Tripartite motif-containing Motif 5 is a protein that in humans is encoded by the TRIM5 gene.It is a 493 amino acids protein that belongs to the TRIM/RBCC family.It contains 1 B box-type zinc finger, 1 B30.2/SPRY domain and 1 RING-type zinc finger. TRIM5 present in the cytoplasm recognizes motifs within the capsid proteins and interferes with the uncoating process, therefore preventing successful reverse transcription and transport to the nucleus of the viral genome. The exact mechanism of action has not been shown conclusively, but capsid protein from restricted viruses is removed by proteasome-dependent degradation
- 分子量
- 30.8 kDa
- UniProt
- Q9C035
- 途径
- Activation of Innate immune Response
-
