Thymic Stromal Lymphopoietin Protein (TSLP) (His tag)
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- 抗原 See all Thymic Stromal Lymphopoietin (TSLP) 蛋白
- Thymic Stromal Lymphopoietin (TSLP)
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This Thymic Stromal Lymphopoietin protein is labelled with His tag.
- 原理
- Recombinant Mouse TSLP Protein (His Tag)(Active)
- 序列
- Met 1-Glu 140
- 产品特性
- A DNA sequence encoding the mouse TSLP (Q9JIE6) (Met 1-Glu 140) was expressed, with a C-terminal polyhistidine tag.
- 纯度
- > 90 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to bind human IL7RA-his in functional ELISA.
- Top Product
- Discover our top product TSLP 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Thymic Stromal Lymphopoietin (TSLP)
- 别名
- TSLP (TSLP 产品)
- 别名
- TSLP Protein, thymic stromal lymphopoietin Protein, TSLP Protein, Tslp Protein
- 背景
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Background: Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is a cytokine expressed by epithelial cells, including keratinocytes, and is important in allergic inflammation. Subsequent studies have shown that TSLP promotes T helper type 2 (TH2) cell responses associated with immunity to some helminth parasites and the pathogenesis of many inflammatory diseases, including atopic dermatitis and asthma. TSLP can promote TH2 cytokine-associated inflammation by directly promoting the effector functions of CD4+ TH2 cells, basophils and other granulocyte populations while simultaneously limiting the expression of DC-derived proinflammatory cytokines and promoting regulatory T cell responses in peripheral tissues.
Synonym: Thymic stromal lymphopoietin;Thymic stroma-derived lymphopoietin;Tslp;TSLP
- 分子量
- 15.4 kDa
- UniProt
- Q9JIE6
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