电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Thymic Stromal Lymphopoietin Protein (TSLP) (His tag)

TSLP 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
产品编号 ABIN7198241
发货至: 中国
  • 抗原 See all Thymic Stromal Lymphopoietin (TSLP) 蛋白
    Thymic Stromal Lymphopoietin (TSLP)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 25
    • 9
    • 5
    • 3
    小鼠
    资源
    • 17
    • 16
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This Thymic Stromal Lymphopoietin protein is labelled with His tag.
    原理
    Recombinant Mouse TSLP Protein (His Tag)(Active)
    序列
    Met 1-Glu 140
    产品特性
    A DNA sequence encoding the mouse TSLP (Q9JIE6) (Met 1-Glu 140) was expressed, with a C-terminal polyhistidine tag.
    纯度
    > 90 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Biological Activity Comment
    Measured by its ability to bind human IL7RA-his in functional ELISA.
    Top Product
    Discover our top product TSLP 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Thymic Stromal Lymphopoietin (TSLP)
    别名
    TSLP (TSLP 产品)
    别名
    TSLP Protein, thymic stromal lymphopoietin Protein, TSLP Protein, Tslp Protein
    背景

    Background: Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is a cytokine expressed by epithelial cells, including keratinocytes, and is important in allergic inflammation.  Subsequent studies have shown that TSLP promotes T helper type 2 (TH2) cell responses associated with immunity to some helminth parasites and the pathogenesis of many inflammatory diseases, including atopic dermatitis and asthma. TSLP can promote TH2 cytokine-associated inflammation by directly promoting the effector functions of CD4+ TH2 cells, basophils and other granulocyte populations while simultaneously limiting the expression of DC-derived proinflammatory cytokines and promoting regulatory T cell responses in peripheral tissues.

    Synonym: Thymic stromal lymphopoietin;Thymic stroma-derived lymphopoietin;Tslp;TSLP

    分子量
    15.4 kDa
    UniProt
    Q9JIE6
You are here: