Thymic Stromal Lymphopoietin Protein (TSLP) (His tag)
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- 抗原 See all Thymic Stromal Lymphopoietin (TSLP) 蛋白
- Thymic Stromal Lymphopoietin (TSLP)
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 人细胞
- 标记
- This Thymic Stromal Lymphopoietin protein is labelled with His tag.
- 原理
- Recombinant Human TSLP (C-10His)
- 序列
- Tyr29-Gln159
- 产品特性
- Recombinant Human Thymic Stromal lymphopoietin is produced by our Mammalian expression system and the target gene encoding Tyr29-Gln159 is expressed with a 10His tag at the C-terminus.
- 纯度
- >95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Loaded Human TSLP-His(Cat#C00K) on HIS1K Biosensor, can bind Human TSLP R-Fc(Cat#CW56) with an affinity constant of 37.97nM as determined in BLI assay
- Top Product
- Discover our top product TSLP 蛋白
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Thymic Stromal Lymphopoietin (TSLP) (AA 29-159) protein (His-Avi Tag)
TSLP 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Thymic Stromal Lymphopoietin (TSLP) (Arg127Ala-Mutant), (Arg130Ala-Mutant) protein (His-Avi Tag,Biotin)TSLP 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Thymic Stromal Lymphopoietin (TSLP) (Arg127Ala-Mutant), (Arg130Ala-Mutant) protein (His-Avi Tag)TSLP 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Thymic Stromal Lymphopoietin (TSLP) (AA 29-159) protein (His tag)TSLP 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Thymic Stromal Lymphopoietin (TSLP) (Active) protein (His tag)TSLP 宿主: Cynomolgus 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by reducing SDS-PAGE. Active
Thymic Stromal Lymphopoietin (TSLP) (AA 29-159) (Active) protein (His tag)TSLP 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Thymic Stromal Lymphopoietin (TSLP) (AA 29-159) (Active) protein (His tag,AVI tag,Biotin)TSLP 宿主: 人 宿主: HEK-293 Cells Recombinant >85 % as determined by SDS-PAGE. Active
Thymic Stromal Lymphopoietin (TSLP) (Active) proteinTSLP 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Thymic Stromal Lymphopoietin (TSLP) protein (Fc Tag)TSLP 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Thymic Stromal Lymphopoietin (TSLP) (AA 28-159) protein (His tag)TSLP 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Thymic Stromal Lymphopoietin (TSLP)
- 别名
- TSLP (TSLP 产品)
- 别名
- TSLP Protein, thymic stromal lymphopoietin Protein, TSLP Protein, Tslp Protein
- 背景
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Background: Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral mucosa, skin and in salivary glands. In aa sequence level, Human TSLP displays about 43 % identity with mouse TSLP.TSLP is a cytokine that functions mainly on myeloid cells, it induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells.TSLP has proliferative effects on the myeloid cell line and may initiate asthma or atopic dermatitis responses by directly activating mast cells . TSLP signals cells via the interleukin-7 receptor-α chain (IL-7Rα),shared with IL-7, together with the TSLP receptor (TSLPR) subunit. Recent studies indicate that TSLP and its receptor are novel therapeutic targets for rheumatoid arthritis,for increased intraarticular TSLP concentrations in patients has caused chemotaxis and activation of arthritogenic T cells.
Synonym: Thymic stromal lymphopoietin, TSLP
- 分子量
- 16.3 kDa
- UniProt
- Q969D9
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