Thimet Oligopeptidase 1 Protein (THOP1) (His tag)
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- 抗原 See all Thimet Oligopeptidase 1 (THOP1) 蛋白
- Thimet Oligopeptidase 1 (THOP1)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Thimet Oligopeptidase 1 protein is labelled with His tag.
- 原理
- Recombinant Human THOP1 Protein (His Tag)
- 序列
- Lys2-Cys689
- 产品特性
- Recombinant Human Thimet Oligopeptidase is produced by our E.coli expression system and the target gene encoding Lys2-Cys689 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product THOP1 蛋白
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Thimet Oligopeptidase 1 (THOP1) (AA 1-689) protein (GST tag)
THOP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Thimet Oligopeptidase 1 (THOP1) (AA 255-354) protein (GST tag)THOP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Thimet Oligopeptidase 1 (THOP1) (Active) protein (His tag)THOP1 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE Active
Thimet Oligopeptidase 1 (THOP1) (AA 1-689) protein (Strep Tag)Crystallography grade THOP1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Thimet Oligopeptidase 1 (THOP1) (AA 1-687) protein (Strep Tag)Crystallography grade THOP1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Thimet Oligopeptidase 1 (THOP1) protein (Myc-DYKDDDDK Tag)THOP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 100 mM NaCl, 10 % Glycerol, pH 7.0.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- Thimet Oligopeptidase 1 (THOP1)
- 别名
- THOP1 (THOP1 产品)
- 别名
- EP24.15 Protein, MEPD_HUMAN Protein, MP78 Protein, TOP Protein, AI131655 Protein, AI327041 Protein, THOP1 Protein, thop1 Protein, MGC147297 Protein, LOC397806 Protein, mepd Protein, thimet oligopeptidase 1 Protein, thimet oligopeptidase 1 L homeolog Protein, thimet oligopeptidase Protein, peptidase Protein, Thimet oligopeptidase Protein, THOP1 Protein, Thop1 Protein, thop1 Protein, thop1.L Protein, Tc00.1047053506411.10 Protein, Tc00.1047053511237.10 Protein, Noca_4613 Protein, ANI_1_1400064 Protein, MBOO_RS10705 Protein, AOR_1_880174 Protein, AnaeK_0425 Protein, MPAL_RS03920 Protein, Hoch_5061 Protein, mepd Protein
- 背景
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Background: Thimet Oligopeptidase (THOP1) belongs to the peptidase M3 family which includes neurolysin and mitochondrial intermediate peptidase. THOP1 is located in Cytoplasm. THOP1 is widely expressed in human tissues and can detected in different subcellular locations. THOP1 is preferential cleavage for bonds with hydrophobic residues at P1, P2 and P3' and a small residue at P1' in substrates of 5 to 15 residues. THOP1 is involved in the metabolism of neuropeptides under 20 amino acid residues and degradation of cytoplasmic peptide. In addition, THOP1 also can degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.
Synonym: Thimet Oligopeptidase, Endopeptidase 24.15, MP78, THOP1
- 分子量
- 80.0 kDa
- UniProt
- P52888
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