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Syndecan 1 Protein (SDC1) (His tag)

SDC1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant (76+20) % as determined by SDS-PAGE
产品编号 ABIN7321114
发货至: 中国
  • 抗原 See all Syndecan 1 (SDC1) 蛋白
    Syndecan 1 (SDC1)
    蛋白类型
    Recombinant
    宿主
    • 23
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠
    资源
    • 18
    • 11
    • 4
    • 4
    • 3
    • 1
    HEK-293 Cells
    标记
    This Syndecan 1 protein is labelled with His tag.
    原理
    Recombinant Rat Syndecan-1/SDC1 Protein (His Tag)
    序列
    Met1-Lys253
    产品特性
    A DNA sequence encoding the rat SDC1 (P26260) (Met1-Lys253) was expressed with a polyhistidine tag at the C-terminus.
    纯度
    (76+20) % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method
    Top Product
    Discover our top product SDC1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Syndecan 1 (SDC1)
    别名
    Syndecan-1/SDC1 (SDC1 产品)
    别名
    CG10497 Protein, CT27296 Protein, Dmel\\CG10497 Protein, Dsyn Protein, Syd Protein, Syn Protein, dSdc Protein, l(2)10608 Protein, sdc Protein, syd Protein, syn Protein, Syn1 Protein, cd138 Protein, synd1 Protein, xSyn1 Protein, syndecan1 Protein, Syndecan-1 Protein, XSyndecan-1 Protein, SDC1 Protein, CD138 Protein, SDC Protein, SYND1 Protein, syndecan Protein, AA408134 Protein, AA409076 Protein, Sstn Protein, Synd Protein, Synd1 Protein, syn-1 Protein, HSPG Protein, SYNDECA Protein, Syndecan Protein, Syndecan Protein, syndecan 1 Protein, Sdc Protein, sdc1 Protein, SDC1 Protein, Sdc1 Protein
    背景

    Background: Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic development. Syndecan-1/SDC1/CD138 has been shown to mediate cell adhesion to several ECM molecules, and to act as a coreceptor for fibroblast growth factors, potent angiogenic growth factors involved also in differentiation. Syndecan-1/SDC1/CD138 expression is reduced during malignant transformation of various epithelia, and this loss correlates with the histological differentiation grade of squamous cell carcinomas, lacking from poorly differentiated tumours. In squamous cell carcinomas of the head and neck, positive syndecan-1 expression correlates with a more favourable prognosis. Experimental studies on the role of Syndecan-1 in malignant transformation have shown that Syndecan-1/SDC1/CD138 expression is associated with the maintenance of epithelial morphology, anchorage-dependent growth and inhibition of invasiveness in vitro.

    Synonym: SDC1,Synd1,CD138

    分子量
    25.6 kDa
    UniProt
    P26260
    途径
    Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism
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