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Syndecan 1 Protein (SDC1) (AA 23-254) (Fc Tag,AVI tag,Biotin)

SDC1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
产品编号 ABIN6973274
发货至: 中国
  • 抗原 See all Syndecan 1 (SDC1) 蛋白
    Syndecan 1 (SDC1)
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 23-254
    宿主
    • 22
    • 9
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 18
    • 11
    • 4
    • 4
    • 3
    • 1
    HEK-293 Cells
    标记
    This Syndecan 1 protein is labelled with Fc Tag,AVI tag,Biotin.
    序列
    AA 23-254
    特异性
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    产品特性
    Biotinylated Human Syndecan-1 Protein, His,Avitag™
    纯度
    >90 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product SDC1 蛋白
  • 说明

    Ready-to-use Avitag™ biotinylated protein:
    The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -20 °C
  • 抗原
    Syndecan 1 (SDC1)
    别名
    Syndecan-1 (SDC1 产品)
    别名
    CG10497 Protein, CT27296 Protein, Dmel\\CG10497 Protein, Dsyn Protein, Syd Protein, Syn Protein, dSdc Protein, l(2)10608 Protein, sdc Protein, syd Protein, syn Protein, Syn1 Protein, cd138 Protein, synd1 Protein, xSyn1 Protein, syndecan1 Protein, Syndecan-1 Protein, XSyndecan-1 Protein, SDC1 Protein, CD138 Protein, SDC Protein, SYND1 Protein, syndecan Protein, AA408134 Protein, AA409076 Protein, Sstn Protein, Synd Protein, Synd1 Protein, syn-1 Protein, HSPG Protein, SYNDECA Protein, Syndecan Protein, Syndecan Protein, syndecan 1 Protein, Sdc Protein, sdc1 Protein, SDC1 Protein, Sdc1 Protein
    背景
    Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. This chaperone activity is important to sustain normal SNARE-complex assembly during aging. Plays also a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity.
    分子量
    52.0 kDa
    途径
    Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism
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