STAT5B Protein (His tag)
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- 抗原 See all STAT5B 蛋白
- STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This STAT5B protein is labelled with His tag.
- 原理
- Recombinant Human STAT5B Protein (His Tag)
- 序列
- Met 1-Thr321
- 产品特性
- Recombinant Human Signal Transducer and Activator of Transcription 5B is produced by our E.coli expression system and the target gene encoding Met1-Thr321 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 1-321) protein (His tag)
STAT5B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 1-390) protein (GST tag)STAT5B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 678-787) protein (GST tag)STAT5B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 1-787) protein (Strep Tag)Crystallography grade STAT5B 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 1-786) protein (Strep Tag)Crystallography grade STAT5B 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Signal Transducer and Activator of Transcription 5B (STAT5B) protein (Myc-DYKDDDDK Tag)STAT5B 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of PBS, 50 % Glycerol, 1 mM DTT, pH 7.4.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))
- 别名
- STAT5B (STAT5B 产品)
- 别名
- STAT5 Protein, stat5 Protein, STAT5A Protein, STAT5B Protein, signal transducer and activator of transcription 5B Protein, signal transducer and activator of transcription 5B S homeolog Protein, Signal transducer and activator of transcription 5B Protein, STAT5B Protein, Stat5b Protein, stat5b.S Protein, LOC490969 Protein, sta5b Protein, LOC100566752 Protein, LOC100052954 Protein
- 背景
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Background: Signal Transducer and Activator of Transcription 5b (STAT5B) is a member of the STAT family of transcription factors. They are responsible for an array of cellular activities including regulating growth, survival, differentiation, motility, and the immune response. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. Signal transduction and activator of transcription 5 (STAT5) is a member of the Jak/STAT signal transduction pathway and is activated by a variety of cytokines (IL22, IL6). STAT5 has two isoforms (A and B) that share 93 % amino acid identity and bind the DNA consensus site TTCN3GAA. STAT5 mediates cytokine signaling by acting as a signal transducer in the cytoplasm and, upon phosphorylation, translocates to the nucleus and activates transcription of specific genes. STAT5 is involved in a wide array of biological processes ranging from regulating apoptosis to adult mammary gland proliferation, differentiation and survival.
Synonym: Signal Transducer and Activator of Transcription 5B, STAT5B
- 分子量
- 38.4 kDa
- UniProt
- P51692
- 途径
- JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
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