SERPINB9 Protein (His tag)
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- 抗原 See all SERPINB9 蛋白
- SERPINB9 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9))
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- 人细胞
- 标记
- This SERPINB9 protein is labelled with His tag.
- 原理
- Recombinant Human SERPINB9/PI-9 Protein (Human Cells, His Tag)
- 序列
- Met 1-Pro376
- 产品特性
- Recombinant Human Serine Protease Inhibitor-clade B9 is produced by our Mammalian expression system and the target gene encoding Met1-Pro376 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SERPINB9 蛋白
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serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) (AA 66-328) protein (His tag)
SERPINB9 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) (AA 279-375) protein (GST tag)SERPINB9 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) (AA 1-376) protein (GST tag)SERPINB9 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) protein (Myc-DYKDDDDK Tag)SERPINB9 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SERPINB9 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9))
- 别名
- SERPINB9/PI-9 (SERPINB9 产品)
- 别名
- SERPINB9 Protein, BB283241 Protein, CAP-3 Protein, CAP3 Protein, PI-9 Protein, PI9 Protein, Spi6 Protein, ovalbumin Protein, serpin family B member 9 Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 9 Protein, serine (or cysteine) peptidase inhibitor, clade B, member 9 Protein, Serpinb9 Protein, SERPINB9 Protein
- 背景
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Background: Serpin B9, also known as Cytoplasmic antiproteinase 3(CAP-3), is a cytoplasm protein which belongs to the large superfamily of serine proteinase inhibitors (serpins), which bind to and inactivate serine proteinases. Serpin B9 is an inhibitor of the granzyme B/perforin lytic pathway. It is expressed in normal mammary epithelial cells but not in most mammary carcinoma cell lines. These interactions are involved in many cellular processes, including coagulation, fibrinolysis, complement fixation, matrix remodeling, and apoptosis. Serpin-B9 expression in immune-privileged cells, APCs, and CTLs protects these cells against the actions of granzyme B, and when expressed in tumor cells or virally infected hepatocytes, confers resistance to killing by CTL and NK cells. Expression of increasing levels of Serpin-B9 in target cells may progressively inhibit immune surveillance by blocking NK and CTL-induced cytotoxicity through the perforin / granzyme pathway and then through the Fas / FasL pathway.
Synonym: Cytoplasmic antiproteinase 3,Peptidase inhibitor 9,CAP3,PI-9,Serpin B9
- 分子量
- 43.4 kDa
- UniProt
- P50453
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