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SERPINB4 Protein (His tag)

SERPINB4 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 88 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317326
发货至: 中国
  • 抗原 See all SERPINB4 蛋白
    SERPINB4 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 4 (SERPINB4))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 2
    资源
    • 6
    • 2
    Baculovirus infected Insect Cells
    标记
    This SERPINB4 protein is labelled with His tag.
    原理
    Recombinant Human SerpinB4 Protein (His Tag)
    序列
    Met 1-Pro 390
    产品特性
    A DNA sequence encoding the human SERPINB4 (P48594) (Met 1-Pro 390) was expressed, with a polyhistidine tag at the N-terminus.
    纯度
    > 88 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product SERPINB4 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 20 % glycerol, 1 mM EDTA, 1 mM DTT
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    SERPINB4 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 4 (SERPINB4))
    别名
    SerpinB4 (SERPINB4 产品)
    别名
    LEUPIN Protein, PI11 Protein, SCCA-2 Protein, SCCA1 Protein, SCCA2 Protein, serpinb4 Protein, serpin family B member 4 Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 4 L homeolog Protein, SERPINB4 Protein, serpinb4.L Protein
    背景

    Background: Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells. Uracil-DNA glycosylase exists in two forms: mitochondrial uracil-DNA glycosylase 1 (UNG1) and nuclear uracil-DNA glycosylase 2 (UNG2). uracil-DNA glycosylase. This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. Defects in UNG are a cause of immunodeficiency with hyper-IgM type 5 (HIGM5). A rare immunodeficiency syndrome characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE. It results in a profound susceptibility to bacterial infections.

    Synonym: LEUPIN,PI11,SCCA-2,SCCA1,SCCA2

    分子量
    47.1 kDa
    UniProt
    P48594
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