SERPINB4 蛋白
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- 抗原 See all SERPINB4 蛋白
- SERPINB4 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 4 (SERPINB4))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product SERPINB4 蛋白
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serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 4 (SERPINB4) (AA 1-390) protein (His tag)
SERPINB4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 4 (SERPINB4) protein (His tag)SERPINB4 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 4 (SERPINB4) proteinSERPINB4 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 4 (SERPINB4) protein (Myc-DYKDDDDK Tag)SERPINB4 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Tris-HCl (pH 7.4 +/- 0.2) with 0.02 % NaN3.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 储存条件
- 4 °C
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- 抗原
- SERPINB4 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 4 (SERPINB4))
- 别名
- SCCA2 / SerpinB4 (SERPINB4 产品)
- 别名
- LEUPIN Protein, PI11 Protein, SCCA-2 Protein, SCCA1 Protein, SCCA2 Protein, serpinb4 Protein, serpin family B member 4 Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 4 L homeolog Protein, SERPINB4 Protein, serpinb4.L Protein
- 背景
- Squamous cell carcinoma antigen (SCCA) is a member of the ovalbumin family of serine proteinase inhibitors (serpins). SCCA is detected in the superficial and intermediate layers of normal squamous epithelium, whereas the mRNA is detected in the basal and subbasal levels. A neutral form of the protein (SCCA1, or SERPINB3) is found in normal and some malignant squamous cells, whereas an acidic form (SCCA2, or SERPINB4) is detected exclusively in tumor cells and in the circulation of patients with squamous cell tumors. SCCA1 shares 92 % amino acid identity with SCCA2. Thus, the appearance of the acidic fraction of SCCA is correlated with more aggressive tumors. Ray et al. (2005) proposed that IL-4- and IL-13-stimulated SCCA gene expression is mediated via STAT-1 and STAT-6 activation, and by suppressing the production, and most likely by interfering with the signaling of these cytokines, UG inhibits SCCA gene expression associated with airway inflammation in asthma.
- 分子量
- 48 kDa
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