SERPINB3 Protein (His tag)
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- 抗原 See all SERPINB3 蛋白
- SERPINB3 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3))
- 蛋白类型
- Recombinant
- 宿主
- 小鼠
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资源
- Baculovirus infected Insect Cells
- 标记
- This SERPINB3 protein is labelled with His tag.
- 原理
- Recombinant Mouse SerpinB3/SCCA1 Protein (His Tag)
- 序列
- Met 1-Pro 386
- 产品特性
- A DNA sequence encoding the mouse SERPINB3C (NP_958751.2) (Met 1-Pro 386) was expressed, with a C-terminal polyhistidine tag.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product SERPINB3 蛋白
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serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3) (AA 276-390) protein (GST tag)
SERPINB3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3) (AA 1-390) protein (His tag)SERPINB3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3) (AA 1-390) protein (GST tag)SERPINB3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3) protein (Myc-DYKDDDDK Tag)SERPINB3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 50 mM Tris 100 mM NaCl, pH 8.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SERPINB3 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3))
- 别名
- SerpinB3/SCCA1 (SERPINB3 产品)
- 别名
- HsT1196 Protein, SCC Protein, SCCA-1 Protein, SCCA-PD Protein, SCCA1 Protein, T4-A Protein, LEUPIN Protein, PI11 Protein, SCCA-2 Protein, SCCA2 Protein, serpin family B member 3 Protein, serpin family B member 4 Protein, serpin B3 Protein, Somatic cell count Protein, SERPINB3 Protein, SERPINB4 Protein, Serpinb3 Protein, LOC483954 Protein, SCC Protein
- 背景
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Background: Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases (serine protease inhibitors). Over 1000 serpins have been identified. Mouse SerpinB3, also known as Squamous cell carcinoma antigen 1, SCCA-1, SERPINB3, SCCA and SCCA1, is a cytoplasm protein which belongs to the serpin family and Ov-serpin subfamily. SerpinB3 may act as a protease inhibitor to modulate the host immune response against tumor cells. Mouse SerpinB3a and SerpinB3b, but not Serpinb3c, are functional, inhibiting both serine and cysteine proteinases with different inhibitory profiles due to the difference of two amino acids in their reactive site loops. SerpinB3a is ubiquitously expressed in most tissues, whereas expression of SerpinB3b is limited to keratinocytes. SerpinB3a and SerpinB3b may play different roles by inhibiting intrinsic or extrinsic proteinases with different expression distributions and different inhibitory profiles.
Synonym: 1110001H02Rik;1110013A16Rik;Scca2;Serpinb3c;Serpinb4
- 分子量
- 46.5 kDa
- NCBI登录号
- NP_958751
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