RPS6KA2 Protein (GST tag)
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- 抗原 See all RPS6KA2 蛋白
- RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This RPS6KA2 protein is labelled with GST tag.
- 原理
- Recombinant Human RSK3/RPS6KA2 Protein (GST Tag)(Active)
- 序列
- Met 1-Leu 733
- 产品特性
- A DNA sequence encoding the human RPS6KA2 isoform 1 (Q15349-1) (Met 1-Leu 733) was fused with the GST tag at the N-terminus.
- 纯度
- > 84 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- The specific activity was determined to be 41 nmol/min/mg using synthetic RSK peptide (KRRRLSSLRA) as substrate.
- Top Product
- Discover our top product RPS6KA2 蛋白
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Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2) (AA 66-311) protein (His-IF2DI Tag)
RPS6KA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2) (AA 631-733) protein (GST tag)RPS6KA2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2) (AA 1-733) protein (GST tag)RPS6KA2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2) (AA 1-733) protein (Strep Tag)Crystallography grade RPS6KA2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2) (AA 1-733) protein (Strep Tag)Crystallography grade RPS6KA2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)RPS6KA2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 7.0, 20 mM GSH
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))
- 别名
- RSK3/RPS6KA2 (RPS6KA2 产品)
- 别名
- HU-2 Protein, MAPKAPK1C Protein, RSK Protein, RSK3 Protein, S6K-alpha Protein, S6K-alpha2 Protein, p90-RSK3 Protein, pp90RSK3 Protein, 90kDa Protein, D17Wsu134e Protein, Rps6ka-rs1 Protein, Rsk3 Protein, p90rsk Protein, pp90rsk Protein, ribosomal protein S6 kinase A2 Protein, ribosomal protein S6 kinase, polypeptide 2 Protein, Rps6ka2 Protein, RPS6KA2 Protein
- 背景
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Background: Ribosomal protein S6 kinase alpha-2, also known as 90 kDa ribosomal protein S6 kinase 2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, Ribosomal S6 kinase 3, RSK-3, RPS6KA2 and MAPKAPK1C, is a nucleus protein which belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family and S6 kinase subfamily. RPS6KA2 / RSK-3 is expressed in many tissues. Highest expression is in lung and skeletal muscle. The expression of RPS6KA2 reduced proliferation, caused G1 arrest, increased apoptosis, reduced levels of phosphorylated extracellular signal-regulated kinase and altered other cell cycle proteins. RPS6KA2 / RSK-3 contains one AGC-kinase C-terminal domain and two protein kinase domains. It forms a complex with either ERK1 or ERK2 in quiescent cells. It transiently dissociates following mitogenic stimulation. RPS6KA2 / RSK-3 is a serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB. RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 are involved in several pathways central to the carcinogenic process, including regulation of cell growth, insulin, and inflammation.
Synonym: HU-2;MAPKAPK1C;p90-RSK3;pp90RSK3;RSK;RSK3;S6K-alpha;S6K-alpha2
- 分子量
- 110 kDa
- 途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Activation of Innate immune Response, Toll-Like Receptors Cascades
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