PTPN2 Protein (His tag)
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- 抗原 See all PTPN2 蛋白
- PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This PTPN2 protein is labelled with His tag.
- 原理
- Recombinant Human TC-PTP/PTPN2 (C-6His)
- 序列
- Thr2-Asn314
- 产品特性
- Recombinant Human Tyrosine-protein phosphatase non-receptor type 2 is produced by our E.coli expression system and the target gene encoding Thr2-Asn314 is expressed with a 6His tag at the C-terminus.
- 纯度
- >95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PTPN2 蛋白
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Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 1-387) protein (GST tag)
PTPN2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 2-314) (Active) protein (His tag)PTPN2 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE Active
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 1-415) protein (Strep Tag)Crystallography grade PTPN2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (AA 1-406) protein (Strep Tag)Crystallography grade PTPN2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)PTPN2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 300Mm NaCl, 1 mM DTT, 10 % Glycerol, pH 7.4.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))
- 别名
- TC-PTP/PTPN2 (PTPN2 产品)
- 别名
- PTN2 Protein, PTPT Protein, TC-PTP Protein, TCELLPTP Protein, TCPTP Protein, AI325124 Protein, Ptpt Protein, PTP-1B Protein, cb806 Protein, ptpn2 Protein, ptpn2l Protein, wu:fc10h07 Protein, zgc:55339 Protein, zgc:76973 Protein, hm:zeh1546 Protein, zgc:63623 Protein, ptn2 Protein, ptpt Protein, tc-ptp Protein, tcellptp Protein, tcptp Protein, protein tyrosine phosphatase, non-receptor type 2 Protein, protein tyrosine phosphatase, non-receptor type 2 S homeolog Protein, protein tyrosine phosphatase, non-receptor type 2, b Protein, protein tyrosine phosphatase, non-receptor type 2, a Protein, protein tyrosine phosphatase, non-receptor type 2 L homeolog Protein, PTPN2 Protein, Ptpn2 Protein, ptpn2.S Protein, ptpn2b Protein, ptpn2a Protein, ptpn2.L Protein
- 背景
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Background: Tyrosine-protein phosphatase non-receptor type 2 (PTPN2), also known as PTPT and TC-PTP, is an enzyme that removes phosphate groups covalently attached to tyrosine residues in proteins. Members of the protein tyrosine phosphatase ( PTP ) family share a highly conserved catalytic motif, which is essential for the catalytic activity. TC-PTP / PTPN2 is a cytosolic tyrosine phosphatase that functions as a negative regulator of a variety of tyrosine kinases and other signaling proteins. The expression of TC-PTP / PTPN2 plays a role of tumor suppressor and may modulate response to treatment. TC-PTP / PTPN2 is an enzyme that is essential for the proper functioning of the immune system and that participates in the control of cell proliferation, and inflammation.TC-PTP / PTPN2 was identified as a negative regulator of NUP214-ABL1 kinase activity.
Synonym: PTP2, PTPN2, PTPTPTN2, TCELLPTP, TCPTP, TC-PTP
- 分子量
- 37.4 kDa
- UniProt
- P17706
- 途径
- EGFR Signaling Pathway, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling
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