PPM1G Protein (AA 317-546) (His tag)
-
- 抗原 See all PPM1G 蛋白
- PPM1G (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1G (PPM1G))
- 蛋白类型
- Recombinant
- 产品特性
- AA 317-546
-
宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 标记
- This PPM1G protein is labelled with His tag.
- 原理
- Recombinant Human PPM1G/PP2C-gamma Protein (aa 317-546, His Tag)
- 序列
- Met 317-Asp 546
- 产品特性
- A DNA sequence encoding the human PPM1G (O15355) C-terminal fragment (Met 317-Asp 546) was expressed, with a polyhistidine tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PPM1G 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 50 mM Tris, 1 mM DTT, 20 % glycerol, pH 7.5
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- PPM1G (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1G (PPM1G))
- 别名
- PPM1G/PP2C-gamma (PPM1G 产品)
- 别名
- AI385652 Protein, Fin13 Protein, PP2CG Protein, PP2CGAMMA Protein, PPP2CG Protein, protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform Protein, protein phosphatase, Mg2+/Mn2+ dependent 1G Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1G Protein, Ppm1g Protein, PPM1G Protein
- 背景
-
Background: Protein phosphatase 1G; also known as Protein phosphatase 1C; Protein phosphatase 2C isoform gamma; Protein phosphatase magnesium-dependent 1 gamma; PP2C-gamma; PPM1G and PPM1C; is a cytoplasm protein which belongs to the PP2C family. PPM1G / PP2C-gamma is widely expressed. It is most abundant in testis; skeletal muscle; and heart. Alternatively spliced transcript variants encoding the same protein have been described. PP2C family members are known to be negative regulators of cell stress response pathways. PPM1G / PP2C-gamma is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors; which is important for the formation of functional spliceosome. PPM1G / PP2C-gamma also plays a role in regulating cell cycle progression.
Synonym: Protein Phosphatase 1G; Protein Phosphatase 1C; Protein Phosphatase 2C Isoform Gamma; PP2C-Gamma; Protein Phosphatase Magnesium-Dependent 1 Gamma; PPM1G; PP2CG;PP2CGAMMA
- 分子量
- 26.6 kDa
- UniProt
- O15355
-